2′,3′-Di-O-acetyl-5′-deoxy-5-fuluro-D-cytidine CAS 161599-46-8

Chemical Name: 2′,3′-Di-O-acetyl-5′-deoxy-5-fuluro-D-cytidine
CAS No.: 161599-46-8
Molecular Fomula: C13H16FN3O6
Molecular weight: 329.28
Appearance: White powder

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2′,3′-Di-O-acetyl-5′-deoxy-5-fluoro-D-cytidine CAS 161599-46-8: Comprehensive User Guide

1. Product Overview & Specifications
2. Applications & Use Cases
3. Client Success Stories
4. Technical Support & Inquiry

1. Product Overview & Specifications

Key Parameters

Parameter	2′,3′-Di-O-acetyl-5′-deoxy-5-fluoro-D-cytidine	Standard 5-Fluorocytidine
CAS Number	161599-46-8	N/A
Molecular Formula	C₁₂H₁₄FN₃O₆	C₉H₁₂FN₃O₅
Purity	≥98% (HPLC)	≥95%
Storage	-20°C, desiccated	2-8°C

Advantages: Enhanced stability due to acetyl protection, improved solubility in organic solvents, and optimized bioavailability for preclinical studies.

2. Applications & Use Cases

Primary Applications

Anticancer Drug Development: Serves as a critical intermediate in capecitabine synthesis.
Antiviral Research: Used in nucleotide analog studies targeting RNA viruses.
Biochemical Probes: Fluorine labeling enables metabolic pathway tracing in cell assays.

Case Study: Oral Chemotherapy Formulation

A pharmaceutical company utilized this compound to develop an orally bioavailable prodrug, achieving 40% higher tumor inhibition rates in murine models compared to IV alternatives.

3. Client Success Stories

Case 1: OncoPharm Therapeutics

Challenge: Needed stable 5-fluoro derivatives for GI-targeted delivery.
Solution: Our acetyl-protected compound demonstrated 72% lower degradation in simulated gastric fluid.
Outcome: Accelerated Phase I trials by 5 months.

Case 2: ViruStop Biologics

Challenge: Required nucleoside analogs with enhanced cellular uptake.
Solution: The lipophilic acetyl groups improved membrane permeability by 3.1-fold.
Outcome: Achieved EC₅₀ of 0.8μM against SARS-CoV-2 in Vero E6 cells.

4. Technical Support & Inquiry

Our team provides:

HPLC/HNMR validation reports
Custom synthesis (mg to kg scale)
Regulatory support (DMF filings)

Contact Our Experts:
Email: info@vivalr.com
Phone: (86) 15866781826

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2′,3′-Di-O-acetyl-5′-deoxy-5-fuluro-D-cytidine CAS 161599-46-8

2′,3′-Di-O-acetyl-5′-deoxy-5-fluoro-D-cytidine CAS 161599-46-8: Comprehensive User Guide

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