2-Chloropyrazine (CAS 14508-49-7): Comprehensive Product Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | 2-Chloropyrazine | Industry Benchmark |
|---|---|---|
| CAS Number | 14508-49-7 | N/A |
| Molecular Formula | C4H3ClN2 | Pyrazine derivatives |
| Molecular Weight | 114.53 g/mol | 100-150 g/mol |
| Density | 1.28-1.30 g/cm³ | 1.2-1.5 g/cm³ |
| Boiling Point | 153-154°C | 150-200°C |
| Flash Point | 57.8°C | 50-60°C |
| Purity Grade | ≥98% (HPLC) | ≥95% |
Safety Data: Classified as flammable liquid (GHS Category 3), with skin/eye irritation warnings (H315, H319). Storage recommendation: 2-8°C under inert atmosphere.
2. Key Applications
Pharmaceutical Intermediates
Widely used in synthesizing active compounds for cardiovascular drugs and central nervous system therapeutics due to its pyrazine backbone.
Agrochemical Development
Serves as precursor for pesticides and herbicides requiring chlorinated heterocyclic structures.
Flavor & Fragrance Industry
Enables production of aroma compounds through nucleophilic substitution reactions.
Material Science
Used in coordination chemistry to create metal-organic frameworks (MOFs) with tailored porosity.
3. Industrial Use Cases
Case 1: Antihypertensive Drug Synthesis
Used as key intermediate in 6-step synthesis of pyrazinamide derivatives, achieving 92% yield under optimized conditions.
Case 2: Ligand Preparation
Facilitated creation of bidentate ligands for palladium-catalyzed cross-coupling reactions in OLED material production.
4. Client Success Stories
MedChemExpress (MCE)
Application: Supplied 98% purity grade material for high-throughput screening of kinase inhibitors.
Volume: 5kg annual procurement
Result: Enabled identification of 3 lead compounds with IC50 < 100nM
Leyan Chemical
Application: Custom synthesis of fluorinated pyrazine derivatives for agrochemical research
Scale: Batch production of 500kg
Outcome: Achieved 99.7% purity with <0.1% residual solvent content
5. Inquiry Guidance
For technical specifications, bulk pricing, or custom synthesis requirements:
Email: info@vivalr.com
Tel: (86) 15866781826
Available packaging: 100g, 500g, 1kg, and custom batch sizes. SDS and CoA provided with all orders.



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