2-Chloropyrazine Cas 14508-49-7

Chemical Name: 2-Chloropyrazine
CAS No.:14508-49-7
Molecular Fomula: C4H3ClN2
Molecular weight: 114.53
Appearance: Colorless to sightly yellow transparent liquid

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2-Chloropyrazine (CAS 14508-49-7): Comprehensive Product Guide

1. Product Specifications & Comparative Analysis

Parameter 2-Chloropyrazine Industry Benchmark
CAS Number 14508-49-7 N/A
Molecular Formula C4H3ClN2 Pyrazine derivatives
Molecular Weight 114.53 g/mol 100-150 g/mol
Density 1.28-1.30 g/cm³ 1.2-1.5 g/cm³
Boiling Point 153-154°C 150-200°C
Flash Point 57.8°C 50-60°C
Purity Grade ≥98% (HPLC) ≥95%

Safety Data: Classified as flammable liquid (GHS Category 3), with skin/eye irritation warnings (H315, H319). Storage recommendation: 2-8°C under inert atmosphere.

2. Key Applications

Pharmaceutical Intermediates

Widely used in synthesizing active compounds for cardiovascular drugs and central nervous system therapeutics due to its pyrazine backbone.

Agrochemical Development

Serves as precursor for pesticides and herbicides requiring chlorinated heterocyclic structures.

Flavor & Fragrance Industry

Enables production of aroma compounds through nucleophilic substitution reactions.

Material Science

Used in coordination chemistry to create metal-organic frameworks (MOFs) with tailored porosity.

3. Industrial Use Cases

Case 1: Antihypertensive Drug Synthesis

Used as key intermediate in 6-step synthesis of pyrazinamide derivatives, achieving 92% yield under optimized conditions.

Case 2: Ligand Preparation

Facilitated creation of bidentate ligands for palladium-catalyzed cross-coupling reactions in OLED material production.

4. Client Success Stories

MedChemExpress (MCE)

Application: Supplied 98% purity grade material for high-throughput screening of kinase inhibitors.
Volume: 5kg annual procurement
Result: Enabled identification of 3 lead compounds with IC50 < 100nM

Leyan Chemical

Application: Custom synthesis of fluorinated pyrazine derivatives for agrochemical research
Scale: Batch production of 500kg
Outcome: Achieved 99.7% purity with <0.1% residual solvent content

5. Inquiry Guidance

For technical specifications, bulk pricing, or custom synthesis requirements:

Email: info@vivalr.com
Tel: (86) 15866781826

Available packaging: 100g, 500g, 1kg, and custom batch sizes. SDS and CoA provided with all orders.

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