4-Aminotoluene-3-sulfonic Acid Cas 88-44-8

Chemical Name: 4-Aminotoluene-3-sulfonic acid
CAS No.:88-44-8
Molecular Formula: C7H9NO3S
Molecular weights: 187.22
Appearance: Light gray or off-white powder
Content: ≥98%

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4-Aminotoluene-3-sulfonic Acid (CAS 88-44-8): Comprehensive User Guide

1. Product Overview and Specifications

4-Aminotoluene-3-sulfonic Acid (CAS 88-44-8), also known as 4-Amino-m-toluenesulfonic acid, is an aromatic sulfonic acid derivative with the molecular formula C7H9NO3S. Key technical parameters include:

Parameter Specification
Appearance White to off-white crystalline powder
Purity ≥99% (HPLC)
Melting Point 280-285°C (dec.)
Solubility Soluble in alkaline solutions, sparingly soluble in water
Storage 2-8°C in airtight container

2. Key Applications and Industrial Uses

2.1 Dye Intermediate

Primary use as a coupling component in azo dye synthesis for textiles and paper industries. Enables production of light-fast yellow and orange hues.

2.2 Pharmaceutical Synthesis

Critical intermediate for sulfonamide drugs and specialty APIs. Used in synthesis of COX-2 inhibitors and antimicrobial agents.

3. Parameter Comparison with Similar Compounds

Compound CAS Reactivity Thermal Stability
4-Aminotoluene-3-sulfonic Acid 88-44-8 Moderate High (>250°C)
2-Aminobenzenesulfonic Acid 88-21-1 High Moderate

4. Step-by-Step Usage Guidelines

4.1 Dye Manufacturing Process

  1. Prepare 5% NaOH solution at 40°C
  2. Dissolve compound at 1:5 molar ratio
  3. Maintain pH 8-9 during diazotization

5. Real-World Customer Case Studies

Case 1: European Dyestuff Manufacturer

Challenge: Needed replacement for carcinogenic benzidine-based dyes
Solution: Implemented CAS 88-44-8 in new eco-friendly dye line
Result: Achieved REACH compliance + 18% production efficiency gain

Case 2: Asian API Producer

Challenge: Impurities in sulfa drug intermediate
Solution: Upgraded to 99.5% purity grade
Result: Reduced purification steps by 40%

6. Request a Quote or Technical Support

Contact our chemistry experts for:

  • Custom purity grades (95%-99.9%)
  • Bulk pricing (25kg drum quantities)
  • Regulatory documentation support

Email: info@vivalr.com
Tel: (86) 15866781826

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