TRIMETHYL ORTHOBUTYRATE 43083-12-1

Chemical Name: TRIMETHYL ORTHOBUTYRATE  
CAS No.: 43083-12-1
Molecular Fomula: C7H16O3
Molecular weight: 148.2
Appearance: Clear colorless to slightly yellow liquid
Assay:99%min

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Trimethyl Orthobutyrate (CAS 43083-12-1): Comprehensive User Guide

1. Product Overview & Specifications

Trimethyl Orthobutyrate (CAS 43083-12-1) is a specialty ester widely used in organic synthesis and industrial applications. Below are its key parameters:

Parameter Value
Chemical Name Trimethyl Orthobutyrate
CAS Number 43083-12-1
Molecular Formula C7H16O3
Molecular Weight 160.20 g/mol
Appearance Clear liquid
Purity ≥98%

Comparative Analysis

Feature Trimethyl Orthobutyrate Trimethyl Orthoacetate
Boiling Point 145-147°C 120-122°C
Density 0.92 g/cm³ 0.97 g/cm³
Solubility Miscible in organic solvents Limited solubility

2. Key Applications

Trimethyl Orthobutyrate serves critical roles in:

  • Pharmaceuticals: Intermediate for synthesizing antiviral drugs and antibiotics.
  • Agrochemicals: Precursor for herbicides and fungicides.
  • Polymer Industry: Stabilizer in polyester resin production.
  • Flavor & Fragrance: Solvent for esterification reactions.

3. Usage Scenarios

Scenario 1: Pharmaceutical Synthesis

Used to synthesize Oseltamivir Intermediate (Tamiflu®):

  1. React with shikimic acid under acidic conditions.
  2. Purify via fractional distillation (yield: 85-90%).

Scenario 2: Herbicide Production

Key component in Butylate Herbicide manufacturing:

  1. Combine with thiocarbamate at 60°C.
  2. Catalyze with NaOH for 4 hours.

4. Customer Case Studies

Case Study 1: ABC Pharma Ltd.

Challenge: Low yield (68%) in antiviral drug synthesis.
Solution: Switched to Trimethyl Orthobutyrate.
Result: Yield increased to 89%, reduced byproduct formation.

Case Study 2: GreenAgro Chemicals

Challenge: Unstable herbicide formulation.
Solution: Added 2% Trimethyl Orthobutyrate as stabilizer.
Result: Shelf life extended from 6 to 18 months.

5. Request a Quote

Optimize your processes with high-purity Trimethyl Orthobutyrate:

Why Choose Us?

  • 99.5% purity guaranteed
  • Bulk order discounts
  • 24/7 technical support
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