Benzenesulfonamide CAS 98-10-2

Assay: 99%min
Appearance: White powder
Packaging: 25kg  woven bag
Sample: available
related documents:

COA of Benzenesulfonamide
TDS of Benzenesulfonamide

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Table of Contents

Benzenesulfonamide (CAS 98-10-2) Overview

Benzenesulfonamide (CAS 98-10-2) is an organosulfur compound with molecular formula C6H7NO2S. This white crystalline solid serves as a crucial intermediate in pharmaceutical synthesis and industrial applications.

Key Identifiers:

Property Value
CAS Number 98-10-2
Molecular Weight 157.19 g/mol
Purity ≥99%
Melting Point 150-153°C
Boiling Point 262°C (decomposes)
Solubility Soluble in ethanol, acetone; slightly in water

Technical Specifications & Comparative Analysis

Parameter Benzenesulfonamide Toluenesulfonamide Methanesulfonamide
Molecular Stability High thermal stability Moderate stability Low decomposition temp
Pharmaceutical Compatibility Excellent Good Limited
Reaction Efficiency 90-95% yield 85-88% yield 75-80% yield

Industrial Applications

1. Pharmaceutical Manufacturing

Essential intermediate for:

  • Sulfa drug synthesis (antibiotics)
  • Protease inhibitor development
  • Diuretic formulations

2. Chemical Synthesis

  • Polymer modification agent
  • Cross-linking catalyst
  • Ion-exchange resin production

3. Agricultural Applications

  • Herbicide synergist
  • Fungicide stabilizer

Operational Guidelines

Handling Protocols

  1. Use PPE: Nitrile gloves, chemical goggles
  2. Maintain ventilation <50°C
  3. Store in airtight containers

Reaction Optimization

Application Optimal Temperature Catalyst Ratio
Sulfonylation 80-90°C 1:1.05 molar
Amidation 110-120°C 1:1.2 molar

Industry Case Studies

Case 1: Pharmaceutical Intermediate Production

Client: EuroPharma Solutions

  • Application: Sulfamethoxazole synthesis
  • Volume: 12 metric tons/year
  • Result: 18% cost reduction vs previous suppliers

Case 2: Specialty Polymer Manufacturing

Client: Advanced Polymer Tech

  • Application: High-temp resin modification
  • Usage Rate: 850kg/month
  • Outcome: 22% improvement in thermal stability

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