THEAFLAVIN 3′-O-GALLATE CAS 28543-07-9

Assay: ≥98%
Appearance: Deep red fine powder
Package:25kg/bottle
Sample: Available
related documents:

COA of THEAFLAVIN 3′-O-GALLATE 28543-07-9
TDS of THEAFLAVIN 3′-O-GALLATE 28543-07-9

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THEAFLAVIN 3′-O-GALLATE (CAS 28543-07-9) Overview

A potent tea-derived polyphenol compound with demonstrated bioactivity in:

  • Antioxidant capacity: ORAC value ≥15,000 µmol TE/g
  • Anti-inflammatory applications: TNF-α inhibition >60% at 50µM
  • Metabolic syndrome management: AMPK activation EC50 = 3.2µM

Technical Specifications & Benchmarking

Parameter THEAFLAVIN 3′-O-GALLATE Standard Theaflavins EGCG
Purity ≥98% (HPLC) 40-60% 95-98%
Solubility DMSO >50mg/ml Partial solubility Water soluble
Thermal Stability Stable ≤80°C Degrades at 60°C Stable ≤70°C

Industrial Applications

Pharmaceutical Development

  • Type 2 diabetes management formulations
  • Neuroprotective compound research
  • Oncology adjuvant therapy studies

Cosmeceutical Innovations

  • Anti-aging serums (10-20µg/ml concentration)
  • UV-protection enhancers
  • Collagen synthesis promoters

Optimal Usage Protocols

Research Applications

  • Cell culture: 5-50µM working concentration
  • Animal studies: 10-25mg/kg/day dosage

Formulation Considerations

  • pH stability range: 4.0-6.5
  • Compatible with cyclodextrin encapsulation

Documented Client Success Stories

Case 1: Nutraceutical Manufacturer (Germany)

  • Challenge: Needed stable antioxidant for enteric-coated tablets
  • Solution: 98% pure THEAFLAVIN 3′-O-GALLATE microencapsulation
  • Result: 40% bioavailability improvement vs. standard extracts

Case 2: Dermocosmetic Lab (South Korea)

  • Challenge: Seeking non-irritating anti-aging actives
  • Solution: 0.5% concentration in nano-emulsion system
  • Result: 31% wrinkle depth reduction in 8-week trial

Case 3: Biomedical Research Institute (USA)

  • Challenge: Required AMPK pathway activator with low cytotoxicity
  • Solution: 10µM THEAFLAVIN 3′-O-GALLATE in cell models
  • Result: 85% target activation vs. 62% with metformin control

Technical & Commercial Inquiry

For formulation support or bulk pricing:

Request following information for faster response:

  • Target application sector
  • Required purity level
  • Annual consumption estimate
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