Table of Contents
THEAFLAVIN 3′-O-GALLATE (CAS 28543-07-9) Overview
A potent tea-derived polyphenol compound with demonstrated bioactivity in:
- Antioxidant capacity: ORAC value ≥15,000 µmol TE/g
- Anti-inflammatory applications: TNF-α inhibition >60% at 50µM
- Metabolic syndrome management: AMPK activation EC50 = 3.2µM
Technical Specifications & Benchmarking
| Parameter | THEAFLAVIN 3′-O-GALLATE | Standard Theaflavins | EGCG |
|---|---|---|---|
| Purity | ≥98% (HPLC) | 40-60% | 95-98% |
| Solubility | DMSO >50mg/ml | Partial solubility | Water soluble |
| Thermal Stability | Stable ≤80°C | Degrades at 60°C | Stable ≤70°C |
Industrial Applications
Pharmaceutical Development
- Type 2 diabetes management formulations
- Neuroprotective compound research
- Oncology adjuvant therapy studies
Cosmeceutical Innovations
- Anti-aging serums (10-20µg/ml concentration)
- UV-protection enhancers
- Collagen synthesis promoters
Optimal Usage Protocols
Research Applications
- Cell culture: 5-50µM working concentration
- Animal studies: 10-25mg/kg/day dosage
Formulation Considerations
- pH stability range: 4.0-6.5
- Compatible with cyclodextrin encapsulation
Documented Client Success Stories
Case 1: Nutraceutical Manufacturer (Germany)
- Challenge: Needed stable antioxidant for enteric-coated tablets
- Solution: 98% pure THEAFLAVIN 3′-O-GALLATE microencapsulation
- Result: 40% bioavailability improvement vs. standard extracts
Case 2: Dermocosmetic Lab (South Korea)
- Challenge: Seeking non-irritating anti-aging actives
- Solution: 0.5% concentration in nano-emulsion system
- Result: 31% wrinkle depth reduction in 8-week trial
Case 3: Biomedical Research Institute (USA)
- Challenge: Required AMPK pathway activator with low cytotoxicity
- Solution: 10µM THEAFLAVIN 3′-O-GALLATE in cell models
- Result: 85% target activation vs. 62% with metformin control
Technical & Commercial Inquiry
For formulation support or bulk pricing:
- Email: info@vivalr.com
- Tel: (86) 15866781826
Request following information for faster response:
- Target application sector
- Required purity level
- Annual consumption estimate



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