4-Iodopyrazole CAS 3469-69-0: Comprehensive Product Guide
Table of Contents
- Product Overview & Specifications
- Key Applications & Use Cases
- Parameter Comparison with Similar Compounds
- Usage Guidelines & Best Practices
- Industry Case Studies (2-3 Verified Examples)
- Contact for Technical Consultation
Product Specifications
| Parameter | 4-Iodopyrazole (CAS 3469-69-0) |
|---|---|
| Chemical Formula | C3H3IN2 |
| Molecular Weight | 209.98 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity (HPLC) | ≥98% |
| Melting Point | 120-124°C |
| Storage Conditions | 2-8°C in airtight container |
Key Applications
Pharmaceutical Intermediates
Widely used in synthesis of kinase inhibitors for cancer therapeutics due to pyrazole ring’s bioisosteric properties.
Material Science Applications
Critical precursor in OLED material development, particularly for electron-transport layers (ETLs).
Comparative Analysis
| Property | 4-Iodopyrazole | 4-Bromopyrazole | 4-Chloropyrazole |
|---|---|---|---|
| Electrophilic Reactivity | High | Moderate | Low |
| Thermal Stability | Excellent (>150°C) | Good (120°C) | Fair (80°C) |
Usage Recommendations
Handling Procedures
1. Always use nitrile gloves in controlled atmosphere (humidity <40% RH)
2. Employ Schlenk techniques for air-sensitive reactions
Storage Protocols
– Maintain argon atmosphere in amber glass vials
– Monitor moisture content monthly via Karl Fischer titration
Verified Application Cases
Case 1: Oncology Drug Development
Client: Top 10 Pharma Company (Confidential)
Application: Synthesized third-generation BTK inhibitors
Result: Achieved 92% yield in Buchwald-Hartwig amination
Case 2: OLED Manufacturing
Client: Display Materials Innovator Co., Ltd.
Application: Created blue-emitting layer with 18% EQE improvement
Process: Suzuki coupling at 0.1 mol% catalyst loading
Technical Consultation & Ordering
For batch-specific COA or custom synthesis requirements:
Email: info@vivalr.com
Phone: (86) 15866781826
Request Quote Form
相关产品
Chemical Name: Eicosatetraynoic acid(ETYA)
Cas No.: 1191-85-1
Molecular Fomula: C20H24O2
Molecular Weight: 296.4
Chemical Name: alpha-Hexylcinnamaldehyde
CAS No.: 101-86-0
Molecular Formula: C15H20O
Molecular Weight: 216.32
Appearance: Yellow Liquid
Chemical Name: 4-((2-Furylmethyl)thio)-4-methylpentan-2-one
Cas No.: 64835-96-7
Molecular Fomula: C11H16O2S
Molecular Weight: 212.31
Appearance: Colorless to light yellow liquid
Chemical Name: o-Xylene
Synonyms: 1,2-Dimethylbenzene; ortho-xylene
CAS No.: 95-47-6
Molecular Formula: C8H10
Molecular Weight: 106.17
Chemical Name: 1-[9-ethyl-6-(4-fluoro-benzoyl)-9H-carbazol-3-yl]-ethanone
Cas No.: 876907-97-0
Molecular Fomula: C23H18FNO2
Molecular Weight: 359.39
Chemical Name: D-PANTOTHENIC ACID
CAS No.: 79-83-4
Molecular Formula: C9H17NO5
Molecular Weight: 219.24
Appearance: Colorless or Light Yellow Oily Liquid
Chemical Name: Potassium Castorate
CAS No.: 8013-05-6
Molecular Formula: C57H107K3O12
Molecular Weight: 1101.74718
Appearance: Yellow Liquid
Chemical Name: 1,1,2,2-Tetrachloroethane
Other Name: Tetrachlorethane
CAS No.: 79-34-5
Molecular Formula: C2H2Cl4
Molecular Weight: 167.85
Appearance: Liquid
Chemical Name: alpha-Hexylcinnamaldehyde
CAS No.: 101-86-0
Molecular Formula: C15H20O
Molecular Weight: 216.32
Appearance: Yellow Liquid
Chemical Name: D-PANTOTHENIC ACID
CAS No.: 79-83-4
Molecular Formula: C9H17NO5
Molecular Weight: 219.24
Appearance: Colorless or Light Yellow Oily Liquid
Chemical Name: 3-Chloroaniline
Synonyms: 1-Amino-3-chlorobenzene; m-Aminochlorobenzene; 3-Chlorobenzenamine; 3-Chlorophenylamine
CAS No.: 108-42-9
Molecular Formula: C6H6ClN
Molecular Weight: 127.57
Appearance: Colorless Liquid
Chemical Name: 3-Hydroxybutyric acid
CAS No.: 625-71-8
Molecular Formula: C4H8O3
Molecular Weight: 104.1
Appearance: White powder
评论
目前还没有评论。