(S,S)-2,8-Diazabicyclo[4,3,0]nonane Cas 151213-42-2

Table of Contents

• Product Overview
• Key Parameters & Comparative Analysis
• Applications in Pharmaceutical & Chemical Synthesis
• Usage Guidelines & Safety Protocols
• Industry Case Studies
• Request Custom Synthesis or Bulk Quotes

(S,S)-2,8-Diazabicyclo[4,3,0]nonane (CAS 151213-42-2): Technical Overview

Structural & Chemical Properties

A bicyclic diamine with the molecular formula C₇H₁₄N₂, molecular weight 126.20 g/mol. White to off-white crystalline powder, ≥98% HPLC purity. Storage: 2-8°C in airtight container.

Key Parameters vs. Similar Compounds

*In asymmetric aldol reaction (ref: J. Org. Chem. 2023, 88, 2345-2351)

Pharmaceutical Applications

Core Use Cases

• Chiral auxiliary in API synthesis (e.g., antiviral drugs)
• Ligand for transition metal catalysis (Pd, Cu)
• Building block for macrocyclic compounds

Reaction Optimization Data

Handling & Safety

PPE Requirements: Nitrile gloves, safety goggles. Incompatible with strong oxidizers. LD₅₀ (oral, rat): 650 mg/kg.

Client Success Stories

Case 1: Antiviral Drug Development

Client: Top 10 Pharma Company (Confidential)
Challenge: Achieve >90% ee in nucleoside analog synthesis
Solution: 10 mol% (S,S)-isomer in Cu-catalyzed coupling
Result: 93% yield, 96% ee (Project completed Q3 2023)

Case 2: Academic Research

Client: ETH Zurich – Organic Chemistry Dept.
Application: Synthesis of chiral MOF catalysts
Scale: 500g batch (98.7% purity by NMR)

Contact for Technical Support

Email: info@vivalr.com
Phone: (86) 15866781826
Request: Custom chiral purity (90-99.9% ee), bulk pricing (>1kg)