Ethyl acetoacetate CAS 141-97-9

Appearance: Colorless transparent liquid
Assay: 99%
Packaging: 200kg/ drum
Capacity: 10000MT/year
Sample: Available
related documents:

COA of Ethyl Acetoacetate 141-97-9
TDS of Ethyl Acetoacetate 141-97-9

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Ethyl Acetoacetate (CAS 141-97-9) Comprehensive Guide

Table of Contents

Product Overview

Ethyl acetoacetate (EAA), a colorless liquid with a fruity aroma, serves as a critical intermediate in organic synthesis. Its CAS registry number 141-97-9 identifies this compound composed of molecular formula C6H10O3 and molecular weight 130.14 g/mol. This β-keto ester exhibits keto-enol tautomerism, enabling versatile reactivity.

Key Specifications

Parameter Value
Boiling Point 181°C (lit.)
Melting Point -43°C (keto form)
Density 1.021 g/cm³ at 25°C
Refractive Index n20/D 1.419
Flash Point 84.4°C (closed cup)
Solubility 116 g/L in water (20°C), miscible with organic solvents
Vapor Pressure 1 mmHg at 28.5°C

Industrial Applications

Pharmaceutical Synthesis

As a building block for antimalarials, antibiotics, and vitamin B1 due to its active methylene group.

Agrochemical Production

Key intermediate in manufacturing herbicides and fungicides through condensation reactions.

Flavor & Fragrance

Source of fruit esters in food additives and perfumery components.

Analytical Chemistry

Metal chelator for spectrophotometric determination of copper and iron ions.

Usage Case Studies

Vitamin B1 Synthesis

In thiamine production, EAA undergoes Claisen condensation with α-picoline to form the pyrimidine moiety.

Antimicrobial Formulations

Pharma companies utilize EAA’s biofilm inhibition properties in topical antiseptic preparations.

Client Success Stories

Shanghai PharmaChem Co., Ltd.

Integrated EAA into their antidiabetic drug intermediates production, achieving 15% yield improvement through optimized acetoacetylation.

Guangzhou Aroma Solutions

Developed a peach-flavored food additive using EAA-derived esters, complying with ISO 22000 standards.

Contact for Quotation

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