5-Bromoindole (CAS 10075-50-0): Technical Guide for Industrial Applications
Table of Contents
1. Product Overview & Specifications
Chemical Profile
5-Bromoindole (CAS 10075-50-0) is a halogenated heterocyclic compound with molecular formula C8H6BrN. This amber crystalline solid serves as a critical building block in pharmaceutical and material science industries.
Technical Specifications
| Parameter | Specification | Competitor A | Competitor B |
|---|---|---|---|
| Purity | ≥99.5% | 98.0-99.0% | 97.5-98.5% |
| Melting Point | 92-95°C | 88-92°C | 90-93°C |
2. Key Applications & Industrial Uses
Pharmaceutical Intermediates
Enables synthesis of:
- Serotonin receptor modulators
- Kinase inhibitors (anticancer applications)
- Antiviral compound precursors
3. Operational Guidelines
Handling Protocol
- Store in nitrogen atmosphere at 2-8°C
- Use anhydrous reaction conditions
- Maintain pH 6.5-7.5 in aqueous solutions
4. Implementation Case Studies
Case 1: Anticancer Drug Synthesis
Used in 7-step synthesis of PD-1/PD-L1 inhibitor candidates, achieving 82% overall yield compared to industry-standard 68-72%.
5. Client Success Stories
PharmaCorp Solutions
Reduced production costs by 34% through optimized coupling reactions using our 5-bromoindole in their kinase inhibitor production line.
MaterialTech Innovations
Achieved 15% efficiency improvement in OLED materials by implementing our purification-grade 5-bromoindole in electron transport layers.
Request Custom Specifications
Contact our technical team for bulk pricing or custom synthesis requirements:
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