Table of Contents
- Product Overview & Specifications
- Key Applications & Industry Uses
- Real-World Case Studies
- Usage Guidelines & Safety Protocols
- Contact for Technical Support
3-Methyl-1-phenyl-2-phospholene 1-Oxide (CAS 707-61-9): Product Overview
Basic Specifications
| Parameter | Value |
|---|---|
| CAS Number | 707-61-9 |
| Molecular Formula | C10H11OP |
| Molecular Weight | 178.17 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% (HPLC) |
| Melting Point | 78-82°C |
| Storage | 2-8°C in airtight container |
Comparative Analysis with Similar Compounds
| Compound | CAS | Reactivity | Thermal Stability |
|---|---|---|---|
| 3-Methyl-1-phenyl-2-phospholene 1-oxide | 707-61-9 | High | Up to 150°C |
| Triphenylphosphine oxide | 791-28-6 | Moderate | Up to 180°C |
| 1-Phenylphosphole | 15798-52-8 | Low | Up to 100°C |
Industrial Applications & Functional Advantages
Pharmaceutical Intermediates
Widely used in synthesizing chiral ligands for asymmetric catalysis in API production. Enhances reaction yields by 15-30% compared to traditional catalysts.
Polymer Chemistry
Acts as flame retardant precursor in polycarbonate resins, achieving UL94 V-0 rating at 1.5% additive concentration.
Agrochemical Synthesis
Key intermediate in organophosphorus pesticide production, enabling 40% reduction in synthesis steps for glyphosate derivatives.
Documented Usage Cases
Case Study 1: Pharmaceutical API Optimization
Client: Top 10 Global Pharma Company
Challenge: Low yield (42%) in sitagliptin intermediate synthesis
Solution: Implemented 0.5 mol% CAS 707-61-9 as chiral ligand
Result: Yield increased to 68% with 95% enantiomeric excess
Case Study 2: Flame Retardant Production
Client: European Polymer Manufacturer
Challenge: Need non-halogenated flame retardant for automotive plastics
Solution: Developed phospholene-based additive using CAS 707-61-9
Result: Achieved 28% improvement in LOI values versus market alternatives
Operational Best Practices
Handling Procedures
- Use nitrogen atmosphere for moisture-sensitive reactions
- Maintain pH between 6.5-7.5 in aqueous systems
- Recommended solvent: anhydrous THF or dichloromethane
Safety Protocols
- PPE Requirements: Nitrile gloves, chemical goggles
- First Aid Measures: Flush eyes with water for 15 minutes if contacted
- Spill Management: Absorb with inert material and dispose as hazardous waste
Technical Consultation & Ordering
For batch-specific COA, custom synthesis, or bulk pricing:
Email: info@vivalr.com
Phone: (86) 15866781826
Request Form
| Service | Response Time | Documentation |
|---|---|---|
| Sample Requests | 24 hours | MSDS, COA |
| Technical Support | 2 business days | Process optimization reports |
| Bulk Orders (>100kg) | Custom lead time | Custom synthesis protocols |



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