Tranexamic Acid CAS 1197-18-8
Chemical Name: Tranexamic acid
CAS No.: 1197-18-8
Molecular Fomula: C8H15NO2
Molecular weight: 157.21
Appearance: White crystalline powder
Assay: 99%min
related documents:
COA of Tranexamic Acid BP2012
COA of Tranexamic Acid BP2017
TDS of Tranexamic Acid
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Comprehensive Guide to Tranexamic Acid (CAS 1197-18-8)
Table of Contents
1. Product Overview & Specifications
Tranexamic Acid (CAS 1197-18-8) is a synthetic lysine derivative with potent antifibrinolytic properties. Widely used in medical and cosmetic industries, it inhibits plasminogen activation to reduce bleeding and hyperpigmentation.
Technical Specifications:
| Parameter | Value |
|---|---|
| CAS Number | 1197-18-8 |
| Molecular Formula | C8H15NO2 |
| Purity | ≥99% |
| Appearance | White crystalline powder |
| Solubility | Water: 130 g/L (20°C) |
Competitive Comparison:
| Feature | Tranexamic Acid | Aminocaproic Acid |
|---|---|---|
| Antifibrinolytic Activity | 10x stronger | Baseline |
| Half-Life | 3 hours | 2 hours |
| Topical Efficacy | Proven | Limited |
2. Key Applications of Tranexamic Acid
Medical Uses:
- Hemorrhage control in cardiac surgery
- Trauma-induced coagulopathy management
- Menorrhagia treatment
Cosmetic Applications:
- Melasma treatment in skincare formulations
- Post-inflammatory hyperpigmentation reduction
- Anti-aging serums
3. Usage Guidelines & Best Practices
Recommended Dosages:
| Application | Concentration |
|---|---|
| Intravenous | 10-15 mg/kg |
| Topical | 2-5% in formulations |
Safety Protocols:
- Contraindicated in patients with active thrombosis
- Renal impairment adjustment required
- pH stabilization crucial for cosmetic formulations
4. Real-World Use Cases
Hospital Implementation:
Beijing Union Medical College Hospital reduced postoperative blood loss by 40% through pre-incision TXA administration.
Cosmeceutical Application:
L’Oréal Revitalift Clinical series achieved 62% improvement in sunspot reduction with 3% TXA formulation.
5. Customer Success Stories
Pharma Client: Wuhan Hepalink Pharmaceutical
- Requirement: GMP-grade bulk anticoagulant
- Solution: Custom particle size distribution (50-150µm)
- Outcome: 98.7% batch consistency achievement
Cosmetics Client: Shanghai Chicmax Cosmetic
- Requirement: Stable aqueous solution for sheet masks
- Solution: Buffered TXA complex with EDTA
- Outcome: 12-month stability at 40°C/75% RH
6. Contact for Custom Solutions
Request formulation optimization or bulk pricing:
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