Sodium Sarcosinate (CAS 4316-73-8) Technical Profile
Table of Contents
- Basic Chemical Properties
- Functional Characteristics
- Industrial Applications
- Safety & Regulatory Compliance
- Production Methodology
- Market Availability
Basic Chemical Properties
| Parameter | Value |
|---|---|
| CAS Registry | 4316-73-8 |
| Molecular Formula | C3H6NNaO2 |
| Molecular Weight | 111.08 g/mol |
| Physical State | White crystalline solid/Transparent liquid (aqueous solution) |
| Density | 1.18-1.24 g/cm³ (30-40% solution) |
| Solubility | Highly water-soluble, slightly soluble in ethanol |
| pH Range | ≥12 (aqueous solution) |
Functional Characteristics
- Zwitterionic amino acid surfactant with dual functionality
- Effective antistatic agent (surface resistivity reduction >60%)
- Moderate detergency with pH buffering capacity
- Stable in formulations within pH 5-9 range
- Biodegradability index: >85% in 28 days (OECD 301D)
Industrial Applications
Personal Care Formulations
- Shampoos: Reduces combing force by 40-45% at 0.5-1.5% concentration
- Facial cleansers: Enhances foam stability while maintaining skin pH
- Antiperspirants: Improves active ingredient dispersion
Technical Applications
- Textile processing: Reduces dye migration by 30% in rapid dye fixation
- Metalworking fluids: Provides corrosion inhibition (ASTM D665 B)
- Polymer modification: Lowers surface tension to 32-35 mN/m
Safety & Regulatory Compliance
| Parameter | Specification |
|---|---|
| Acute Oral Toxicity (LD50) | >2,000 mg/kg (OECD 423) |
| Skin Irritation | Non-irritating (OECD 439) |
| Comedogenicity | 0/5 (Friedman-Kligman method) |
| Ecotoxicity (EC50) | >100 mg/L (Daphnia magna) |
Production Methodology
- Base-catalyzed reaction: Methylamine + Chloroacetic Acid → Sarcosine
- Neutralization: Sarcosine + NaOH → Sodium Sarcosinate
- Purification: Crystallization at controlled pH (8.5-9.0)
- Concentration: Vacuum evaporation to 30-40% active content
Market Availability
| Grade | Purity | Packaging |
|---|---|---|
| Cosmetic Grade | ≥99% | 25kg PE drums |
| Technical Grade | 30-40% solution | 200kg HDPE containers |
| Pharmaceutical Grade | USP-NF compliance | Customized packaging |
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