Thioglycolic Acid (CAS 68-11-1): Comprehensive Product Guide
Table of Contents
1. Product Overview & Specifications
Thioglycolic Acid (TGA), CAS 68-11-1, is a sulfur-containing organic compound with the molecular formula C2H4O2S and a molecular weight of 92.12 g/mol. It appears as a colorless to pale yellow liquid with a pungent odor and is highly soluble in water, ethanol, and ether.
| Parameter | Value |
|---|---|
| Boiling Point | 225.5°C (760 mmHg) 96°C (5 mmHg) |
| Melting Point | -16°C |
| Density | 1.326 g/mL (20°C) |
| Flash Point | 126°C (closed cup) |
| pH | 2–3 (1% aqueous solution) |
Comparative Analysis
TGA outperforms similar thiol-based acids in:
- Higher thermal stability in diluted solutions
- Superior reactivity in metal chelation
- Lower volatility compared to mercaptopropionic acid
2. Key Applications
Pharmaceutical Industry
Critical intermediate for:
- Cephalosporin antibiotics synthesis
- Anticancer drug precursors
Cosmetics
- Cold-wave perm solutions (pH 8–9.5 formulations)
- Depilatory agents (5–10% concentration)
Polymer Production
- PVC stabilizer (0.1–0.5% additive)
- Chain transfer agent in acrylic polymerizations
Metal Treatment
- Iron/molybdenum detection reagent
- Surface passivation for corrosion resistance
3. Industry Use Cases
Case A: Textile Manufacturing
Challenge: Improve wool fiber elasticity without chemical degradation
Solution: 8% TGA-based treatment increased tensile strength by 40% while reducing processing time
Case B: PVC Stabilization
Challenge: Replace lead-based stabilizers in food-grade PVC
Solution: TGA-calcium/zinc system achieved UL 94 V-0 flame rating with 300+ hours UV stability
4. Client Success Stories
Jinan Century Chemical Co., Ltd. (Shandong, China)
- Application: Cosmetic depilatory production
- Results: 99.5% purity TGA enabled 18% faster hair dissolution vs. industry average
- Volume: 200 MT/month continuous supply since 2013
Shandong Jinyueyuan New Materials
- Application: PVC pipe stabilization
- Results: 0.3% TGA additive reduced stabilizer costs by 25% while meeting FDA 21 CFR 177.1980
5. Safety & Handling
| Parameter | Requirement |
|---|---|
| Storage Temperature | 2–8°C in sealed containers |
| Shelf Life | 24 months in original packaging |
| PPE | Neoprene gloves, face shield, APR with acid gas cartridges |
Emergency Response: Neutralize spills with sodium bicarbonate (5% solution) followed by 30-minute water flush
6. Contact for Quotations
Request bulk pricing (70+ MT inventory available):
Email: info@vivalr.com
Tel: (86) 15866781826



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