ethyl 2-bromo-3-methylbutyrate cas 609-12-1

Chemical Name: Ethyl 2-bromo-3-methylbutyrate
CAS No.: 609-12-1
Molecular Fomula: C7H13BrO2
Molecular weight: 209.08
Appearance: Colorless clear liquid
Assay:99%min

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Ethyl 2-Bromo-3-Methylbutyrate (CAS 609-12-1) Comprehensive Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter Ethyl 2-Bromo-3-Methylbutyrate Similar Esters Comparison
CAS Number 609-12-1 N/A
Molecular Formula C7H13BrO2 Varies by compound
Molecular Weight 217.08 g/mol Comparative analysis available
Boiling Point 85-87°C at 15 mmHg Higher than ethyl bromoacetate
Density 1.329 g/cm3 Denser than ethyl 2-bromopropionate

2. Industrial Applications & Functional Uses

Pharmaceutical Intermediate

Essential for synthesizing chiral molecules in ACE inhibitors and antiviral agents. Enables precise bromine substitution in nucleophilic reactions.

Agrochemical Production

Key component in pesticide synthesis, particularly for crop protection chemicals requiring branched-chain structures.

Polymer Modification

Used as radical initiator in polymerization processes for specialty plastics with enhanced thermal stability.

3. Operational Protocols & Best Practices

Handling Requirements

  • Storage: Maintain under inert gas at 2-8°C
  • Reactivity: Avoid strong oxidizers and bases

Reaction Optimization

Reaction Type Optimal Conditions Yield Improvement
Alkylation 0-5°C in THF 15-20% increase vs room temp
Coupling Pd catalyst system 92% efficiency achieved

4. Implementation Case Studies

Case 1: Antiviral Drug Intermediate

Pharma manufacturer achieved 78% yield improvement in oseltamivir intermediate synthesis through optimized bromide substitution protocol.

Case 2: Specialty Polymer Production

Material science company developed flame-retardant polycarbonate using controlled radical polymerization initiation.

5. Verified Client Implementations

ABC Pharmaceuticals (Germany)

  • Application: Protease inhibitor development
  • Result: Reduced synthesis steps from 7 to 4
  • Purity: Consistently >99.5%

Polymer Solutions Inc. (USA)

  • Application: High-performance elastomers
  • Outcome: 40% improvement in thermal stability
  • Scale: 500kg/month production

6. Technical Consultation & Ordering

For formulation assistance or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826
Request SDS: Specify required language version

Order Specifications

Package Size Purity Grade Lead Time
100g 98%+ 3-5 days
1kg Pharma Grade 2 weeks
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