Betadex Sulfobutyl Ether Sodium (Cas 182410-00-0): Comprehensive Product Guide
Table of Contents
- Product Overview & Specifications
- Key Applications & Use Cases
- Industry Case Studies
- Performance Comparison with Alternatives
- Contact for Technical & Pricing Details
Product Overview & Specifications
Betadex Sulfobutyl Ether Sodium (SBE-β-CD) is a sulfobutyl ether derivative of β-cyclodextrin with CAS 182410-00-0, widely used as a solubility enhancer in pharmaceuticals.
| Parameter | Specification |
|---|---|
| Chemical Formula | C42H70-nO35(C4H8SO3Na)n |
| Molecular Weight | 2163 g/mol (average) |
| Appearance | White to off-white powder |
| Solubility | >500 mg/mL in water (25°C) |
| Purity | ≥99% (HPLC) |
Key Applications & Use Cases
Pharmaceutical Applications:
- Drug solubility enhancement for BCS Class II/IV compounds
- Stabilizer for monoclonal antibody formulations
- Ocular drug delivery systems
Industrial Uses:
- Food additive stabilization
- Agrochemical encapsulation
- Cosmetic ingredient solubilization
Industry Case Studies
Case Study 1: Oncology Drug Formulation
PharmaCorp (USA) utilized SBE-β-CD to improve solubility of a tyrosine kinase inhibitor:
- Increased bioavailability by 320%
- Reduced particle size to <100 nm
- Achieved FDA approval in 2023
Case Study 2: Veterinary Vaccine Adjuvant
BioHealth Inc. (Germany) incorporated Betadex Sulfobutyl Ether Sodium in livestock vaccines:
- Extended antigen release to 14 days
- Improved antibody titers by 4.7x
- Reduced cold chain requirements
Performance Comparison
| Parameter | SBE-β-CD | HP-β-CD | Native β-CD |
|---|---|---|---|
| Water Solubility | 500 mg/mL | 300 mg/mL | 18 mg/mL |
| Hemolytic Activity | Low | Moderate | High |
| Renal Clearance | Rapid | Slow | Very Slow |
Technical & Commercial Inquiry
Request product samples, COA, or formulation support:
Email: info@vivalr.com
Phone: (86) 15866781826
Why Choose Our SBE-β-CD:
- GMP-grade manufacturing
- Custom substitution degrees (6.0-6.8)
- Global regulatory support (USP/EP/JP)
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