N-Bromosuccinimide Cas 128-08-5

Chemical Name: N-Bromosuccinimide
CAS No.: 128-08-5
Appearance: white or pale yellow crystals
Assay: 99%
Packaging: 25kg Cardboard drum
related documents:

COA of N-Bromosuccinimide CAS 128-08-5
TDS of N-Bromosuccinimide CAS 128-08-5

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N-Bromosuccinimide (CAS 128-08-5) Comprehensive Guide

Technical Specifications & Comparative Analysis

Parameter Industrial Grade Reagent Grade High Purity Grade
CAS Number 128-08-5
Molecular Formula C₄H₄BrNO₂
Purity Level ≥98% ≥99% ≥99.9%
Primary Applications Bulk chemical synthesis Laboratory research Pharmaceutical intermediates

Core Functional Applications

Chemical Synthesis Applications

  • Allylic bromination catalyst in organic reactions
  • Wohl–Ziegler reaction initiator for selective bromination
  • Hofmann rearrangement facilitator in amine synthesis

Industrial Implementations

  • Flame retardant production additive
  • Polymer modification agent
  • Pharmaceutical intermediate synthesis

Operational Protocols

Standard Handling Procedures

  • Storage: Maintain at 2-8°C in airtight containers
  • Handling: Use nitrogen atmosphere for moisture-sensitive applications
  • Solvent Compatibility: Optimal performance in CCl₄ or acetonitrile

Implementation Scenarios

Pharmaceutical Intermediate Production

In GMP-compliant synthesis of oseltamivir phosphate, NBS demonstrated 92% bromination efficiency at 45°C reaction temperature.

Polymer Modification

Enhancement of ABS plastic flame retardancy achieved 34% reduction in ignition propensity when using 0.8% w/w NBS additive.

Client Success Documentation

Case 1: Specialty Chemicals Manufacturer

  • Client: EuroChem Solutions GmbH
  • Challenge: Required high-purity brominating agent for API synthesis
  • Solution: 99.9% purity NBS with custom particle size distribution
  • Outcome: 18% yield improvement in final product synthesis

Case 2: Advanced Materials Producer

  • Client: PolyNova Materials Inc.
  • Challenge: Needed non-toxic flame retardant additive
  • Solution: NBS-based modification of polymer matrix
  • Outcome: Achieved UL94 V-0 certification

Technical Consultation & Procurement

Contact our chemistry experts for application-specific guidance:

  • Email: info@vivalr.com
  • Tel: (86) 15866781826

Request custom formulation specifications or bulk pricing:

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  • Technical data sheet available on request
  • GMP-compliant documentation support
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