Phenylphosphinic acid CAS 1779-48-2

Product Name: Phenylphosphinic acid
CAS No.: 1779-48-2
Molecular formula: C6H7O2P
Molecular weight: 142.09
Appearance: White powder or crystal
Assay: 99.0%

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Table of Contents

Phenylphosphinic Acid (CAS 1779-48-2) Overview

A organophosphorus compound with molecular formula C6H7O2P. Key parameters:

Parameter Value
CAS Number 1779-48-2
Molecular Weight 142.09 g/mol
Appearance White crystalline powder
Purity ≥98%
Melting Point 160-163°C
Solubility Soluble in water, ethanol

Technical Comparison Table

Property Phenylphosphinic Acid Phenylphosphonic Acid Hypophosphites
Thermal Stability 220°C 250°C 180°C
Flame Retardancy (LOI) 32% 28% 25%
Reactivity Moderate High Low

Industrial Applications

1. Flame Retardants

Widely used in engineering plastics (PA, PBT, PET) for UL94 V-0 compliance. Reduces smoke density by 40% compared to traditional additives.

2. Pharmaceutical Intermediates

Critical precursor for antiviral drugs like Foscarnet sodium (HIV treatment) and metal-chelating agents.

3. Coordination Chemistry

Forms stable complexes with transition metals (Cu, Fe, Ni) for catalytic applications in cross-coupling reactions.

Operational Guidelines

Dosage Recommendations

Application Concentration Processing Temp
Polyamide 6 8-12% 260-280°C
Epoxy Resins 15-20% 120-150°C

Safety Protocols

Use PPE (gloves/goggles) when handling. Store in cool (<25°C), dry conditions. LD50 (oral rat): 2300 mg/kg.

Client Implementations

Case 1: German Automotive Supplier

Client: Top 3 automotive polymer manufacturer
Challenge: Achieve UL94 V-0 in thin-wall (0.8mm) connectors
Solution: 10% Phenylphosphinic acid + glass fiber reinforcement
Result: Passed 5VA certification with 28% cost reduction vs brominated systems

Case 2: Indian Pharma Company

Client: API producer for HIV medications
Challenge: Improve synthesis yield of Fosdevir intermediate
Solution: Chelating agent in Grignard reaction
Result: Yield increased from 68% to 82% with 99.5% purity

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