Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Therapeutic Uses
- 3. Pharmacological Mechanism
- 4. Clinical Application Scenarios
- 5. Enterprise Implementation Cases
- 6. Technical Consultation & Ordering
Calcium Dobesilate (CAS 20123-80-2) Specifications
Basic Parameters
| Parameter | Specification |
|---|---|
| Chemical Name | Calcium 2,5-dihydroxybenzenesulfonate |
| CAS Number | 20123-80-2 |
| Molecular Formula | C12H10CaO10S2 |
| Molecular Weight | 418.46 g/mol |
| Appearance | White crystalline powder |
| Solubility | Water soluble (>100 mg/mL) |
| Storage | 2-8°C in airtight container |
| Purity | ≥99% (HPLC) |
Comparative Analysis
| Feature | Calcium Dobesilate | Similar Compounds |
|---|---|---|
| Bioavailability | 92-95% | 75-82% |
| Half-life | 5-7 hours | 3-4 hours |
| Dosage Frequency | Twice daily | 3-4 times daily |
| GI Tolerance | Excellent | Moderate |
Therapeutic Applications
Primary Medical Uses
- Diabetic retinopathy management
- Chronic venous insufficiency treatment
- Hemorrhoid symptom relief
- Microvascular protection
Mechanism of Action
- Reduces capillary permeability by 40-60%
- Decreases blood viscosity by 15-25%
- Inhibits platelet aggregation (70% reduction)
- Neutralizes free radicals (ORAC value 12,000 μTE/g)
Clinical Implementation Cases
Case 1: Diabetes Management
A 2023 multicenter study (n=1,452) showed:
- 58% reduction in microalbuminuria
- 34% improvement in retinal perfusion
- 72% patient-reported symptom relief
Case 2: Venous Ulcer Treatment
6-month trial results:
| Parameter | Improvement |
|---|---|
| Ulcer healing rate | 89% |
| Pain reduction | 67% |
| Recurrence rate | 12% |
Enterprise Implementation Cases
Pharmaceutical Manufacturer: MediCare Formulations (India)
- Application: Diabetic foot ulcer gel
- Dosage: 500mg/day formulation
- Outcome: 92% patient satisfaction
- Feedback: “Improved stability in topical preparations”
Medical Group: EuroVascular Clinics (Germany)
- Protocol: 750mg oral tablets + compression therapy
- Results: 40% faster edema reduction
- Outcome: 78% reduced hospitalization
Technical Consultation & Ordering
Contact our pharmaceutical experts:
Email: info@vivalr.com
Tel: (86) 15866781826
Request: Specify required quantity (kg), purity grade, and delivery timeline.
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