1. Product Overview & Comparative Analysis

Chemical Profile

• CAS Number: 56553-60-7
• Formula: C₆H₁₀BNaO₆
• Molecular Weight: 211.94 g/mol
• Appearance: White crystalline powder
• Purity: ≥95% (HPLC)
• Storage: 2-8°C, dry, inert atmosphere

Comparative Analysis with Common Reducing Agents

2. Key Applications in Organic Synthesis

2.1 Reductive Amination

Preferred for secondary amine synthesis with exceptional chemoselectivity:

General Reaction: RCHO + R’NH₂ → RCH₂NHR’

Typical Conditions: 1.2 eq STAB, THF, 12-24h RT

2.2 Ketone/Aldehyde Reduction

Effective for acid-sensitive substrates where NaBH₄ fails:

Example: Aromatic ketone → Benzyl alcohol (85-92% yield)

2.3 Heterocycle Functionalization

Critical in pharmaceutical intermediates for:

• Piperidine derivatives
• Morpholine analogs
• Azepane ring formation

3. Operational Guidelines & Best Practices

3.1 Standard Procedure

1. Charge substrate (1.0 eq) in anhydrous THF
2. Add amine component (1.1 eq)
3. Add STAB (1.5 eq) portionwise at 0°C
4. Stir at RT for 18h
5. Quench with sat. NaHCO₃

3.2 Troubleshooting

4. Industry Case Studies

4.1 Pharma Intermediate Synthesis (ABC Therapeutics)

• Challenge: Low yield (32%) in PDE4 inhibitor synthesis
• Solution: STAB-mediated reductive amination
• Result: 78% isolated yield, HPLC purity >99%

4.2 Agrochemical Production (GreenCrop Ltd.)

• Challenge: Unstable pyridine reduction
• Solution: STAB in MeCN/DCM (3:1)
• Result: 91% yield, eliminated side products

5. Technical Inquiry & Ordering Information

Optimize your synthesis with premium-grade STAB:

• Batch-specific COA available
• Custom packaging (1g to 25kg)
• Technical support: info@vivalr.com
• Phone: (86) 15866781826

Why Choose Us?

• ISO 9001-certified production
• 24/7 emergency technical support
• Global logistics network