4-Hexylresorcinol (CAS 136-77-6): Technical Guide & Applications
Table of Contents
1. Product Overview & Specifications
| Parameter | 4-Hexylresorcinol | Common Alternatives* |
|---|---|---|
| CAS No. | 136-77-6 | N/A |
| Molecular Formula | C12H18O2 | Hydroquinone: C6H6O2 |
| Molecular Weight | 194.27 g/mol | 110.11 g/mol (Hydroquinone) |
| Melting Point | 65-67°C | 172°C (Hydroquinone) |
| Solubility in Water | 0.05 g/100 mL (18°C) | 5.9 g/100 mL (Hydroquinone) |
| Key Advantage | Safer melanin inhibitor | Higher toxicity risk |
*Comparison with hydroquinone highlights superior safety profile.
2. Key Applications & Functional Properties
2.1 Cosmetic Industry
- Melanin Inhibition: 10x stronger tyrosinase inhibition than arbutin (IC50 = 0.13 μM)
- Antioxidant Efficacy: Reduces oxidative stress via glutathione pathway modulation
2.2 Food Processing
- Shrimp Preservation: Limits melanosis at 1 ppm concentration
- Color Stabilization: Extends product shelf life by 30-40%
2.3 Pharmaceutical Uses
- Anthelmintic agent in veterinary medicine
- Topical antiseptic formulations
3. Industry Use Cases
3.1 Seafood Processing
Applied in shrimp treatment baths (0.25-1.0% solution) to prevent blackspot formation during frozen storage.
3.2 Cosmetic Formulations
Used in serums at 0.5-2% concentration for UV-induced hyperpigmentation correction.
4. Client Success Stories
Case 1: Shandong Zhengsheng Biotechnology
- Challenge: 35% product loss from shrimp discoloration
- Solution: 0.8% 4-hexylresorcinol dip pretreatment
- Result: 92% reduction in waste, ROI achieved in 6 months
Case 2: Hubei Hongxin Ruiyu Fine Chemicals
- Application: Cosmetic whitening agent
- Formulation: 1.5% active in night repair cream
- Clinical Results: 47% melanin reduction vs placebo in 8-week trial
5. Contact for Custom Solutions
Request technical specifications sheets or formulation guidance:
Email: info@vivalr.com
Tel: (86) 15866781826



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