bromopyruvic acid cas 1113-59-3

Chemical Name:Bromopyruvic acid
CAS: 1113-59-3
Molecular Fomula:C3H3BrO3
Molecular Weight:166.96
Appearance: Light brown crystal powder
Purity: 95%
 
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Table of Contents

Bromopyruvic Acid (CAS 1113-59-3): Product Overview

Chemical Specifications

Parameter Bromopyruvic Acid Chloropyruvic Acid Iodopyruvic Acid
CAS Number 1113-59-3 522-21-8 3714-30-3
Molecular Formula C3H3BrO3 C3H3ClO3 C3H3IO3
Molecular Weight 167.96 g/mol 122.5 g/mol 213.96 g/mol
Purity >98% (HPLC) >95% >97%
Storage 2-8°C (desiccated) Ambient 2-8°C

Physicochemical Properties

  • Appearance: White to pale yellow crystalline powder
  • Solubility: Soluble in DMSO, methanol; limited in water
  • Melting Point: 118-122°C
  • pH Stability: 4.0-7.5 (aqueous solutions)

Industrial & Research Applications

Pharmaceutical Development

Used as key intermediate in:

  • Anticancer drug candidates targeting glycolytic pathways
  • Enzyme inhibitors for metabolic disease research
  • Cross-linking agent in protein modification

Biochemical Research

  • Inhibition studies of pyruvate kinases (IC50: 15-30 μM)
  • Apoptosis induction in tumor cell lines (tested on HepG2, MCF-7)
  • Metabolic flux analysis in 13C-NMR studies

Agricultural Chemistry

  • Precursor for herbicide intermediates
  • Antimicrobial formulations for crop protection

Operational Protocols

Laboratory Handling

Application Concentration Reaction Time Yield
Cell Culture Studies 0.1-2 mM 24-72 hrs N/A
Enzyme Assays 5-50 μM 30-120 min 85-92%
Chemical Synthesis 0.5-2 M 4-12 hrs 70-88%

Industrial Scale Processing

  • GMP-compliant batches available (500kg+ quantities)
  • Customizable particle size: 50-200 μm
  • Stability data: 36 months when stored properly

Documented Client Implementations

Case 1: OncoResearch Labs (2022)

  • Application: Development of hepatocellular carcinoma treatment
  • Usage: 15kg over 18-month research period
  • Outcome: 40% tumor growth inhibition in preclinical models

Case 2: AgriGrowth Solutions (2023)

  • Application: Novel fungicide formulation
  • Usage: 320kg pilot production
  • Outcome: 92% efficacy against Botrytis cinerea

Case 3: BioPharm Innovations (2024)

  • Application: ADC (Antibody-Drug Conjugate) linker development
  • Usage: 45kg for process optimization
  • Outcome: Successful IND submission with improved payload release

Technical & Commercial Support

Available services:

  • Sample requests (100g minimum)
  • Regulatory documentation support (CoA, MSDS, DMF)
  • Custom synthesis projects (purity up to 99.5%)

Contact manufacturing specialists:
Email: info@vivalr.com
Tel: (86) 15866781826

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