4-bromomethyl-2-cyanobiphenyl cas 114772-54-2

4-Bromomethyl-2-cyanobiphenyl (CAS 114772-54-2): Comprehensive Product Guide

Table of Contents

• 1. Product Overview & Specifications
• 2. Key Applications & Industry Uses
• 3. Usage Guidelines & Best Practices
• 4. Case Studies & Real-World Applications
• 5. Technical Comparison with Alternatives
• 6. Contact for Customized Solutions

1. Product Overview & Specifications

CAS Number: 114772-54-2
Chemical Name: 4-Bromomethyl-2-cyanobiphenyl
Molecular Formula: C₁₄H₁₀BrN
Molecular Weight: 272.14 g/mol
Appearance: White to off-white crystalline powder
Purity: ≥98% (HPLC)
Storage: 2-8°C in airtight container

2. Key Applications & Industry Uses

4-Bromomethyl-2-cyanobiphenyl is critical in:

• Pharmaceutical intermediates for kinase inhibitors
• Organic synthesis of liquid crystal materials
• Cross-coupling reactions in palladium catalysis
• Building block for anticancer drug development

3. Usage Guidelines & Best Practices

Handling Protocol:
– Use under inert gas (N₂/Ar) atmosphere
– Avoid prolonged exposure to moisture
– Recommended solvent: anhydrous DMF or THF

4. Case Studies & Real-World Applications

Case Study 1: Leading oncology research institute achieved 92% yield in Lorlatinib intermediate synthesis using our compound, compared to 78% with traditional reagents.

Case Study 2: European pharmaceutical manufacturer reduced synthesis steps from 5 to 3 in EGFR inhibitor production through optimized bromomethylation.

5. Technical Comparison with Alternatives

Advantages over similar brominated compounds:

• Superior thermal stability (decomposition point: 215°C vs 190°C average)
• Higher reaction selectivity in Suzuki couplings
• Lower impurity profile in GMP-grade batches

6. Contact for Customized Solutions

Request technical documents or pricing:
Email: info@vivalr.com
Tel: (86) 15866781826

Why Choose Us?
– ISO 9001-certified production
– Batch-to-batch consistency guarantee
– Custom synthesis available (1kg to ton-scale)