Benzimidazole CAS 51-17-2: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Benzimidazole (CAS 51-17-2) is a heterocyclic aromatic compound with the molecular formula C7H6N2 and a molecular weight of 118.14 g/mol. It appears as white crystalline flakes with a melting point of 170–172°C and a boiling point exceeding 360°C.
| Parameter | Benzimidazole | Benzotriazole | Imidazole |
|---|---|---|---|
| CAS Number | 51-17-2 | 95-14-7 | 288-32-4 |
| Solubility | Soluble in hot water, ethanol; insoluble in benzene | Soluble in alkaline solutions | Highly water-soluble |
| Primary Use | Pharmaceutical intermediates | Corrosion inhibition | Organic synthesis |
Key Specifications:
– Purity: 98–99% (industrial/pharmaceutical grade)
– Storage: 2–8°C in airtight containers
– Safety: Non-flammable but may cause eye/skin irritation
2. Key Applications
Pharmaceutical Industry
Core building block for:
– Anthelmintic drugs: Albendazole, Mebendazole
– Proton pump inhibitors: Omeprazole, Pantoprazole
– Antiviral/anticancer drug development
Agricultural Chemistry
– Intermediate for fungicides and pesticides
– Component in plant growth regulators
Material Science
– Precursor for porous polymers (CO2 separation materials)
– Coordination complexes in catalysis
3. Usage Scenarios
Pharmaceutical Synthesis
Example: In omeprazole production:
1. Benzimidazole → Sulfonation → Coupling with pyridine derivative
2. Final purification for acid-resistant enteric coating
Analytical Chemistry
– Colorimetric determination of cobalt ions
– Chelating agent in metal ion chromatography
4. Industry Case Studies
Case 1: Pharmaceutical Manufacturer (Hubei, China)
Challenge: Scale-up of Albendazole production
Solution: Optimized benzimidazole purification (99.5% purity)
Result: 22% yield improvement, meeting WHO GMP standards
Case 2: Polymer Research Lab (Germany)
Application: CO2-selective adsorption membranes
Process: Synthesized benzimidazole-linked polymers (BILPs)
Performance: 93% CO2/N2 selectivity at 25°C
5. Contact Information
For technical specifications, bulk orders, or custom synthesis requirements:
Email: info@vivalr.com
Phone: (86) 15866781826
Availability: 25kg drums; custom packaging available



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