Table of Contents
- Product Overview & Specifications
- Key Applications & Uses
- Implementation Case Studies
- Industry Client Success Stories
- Technical Consultation & Quotation
BSTFA (CAS 25561-30-2) Technical Specifications
Material Characteristics
| Parameter | Specification | Testing Method |
|---|---|---|
| Chemical Name | Bis(trimethylsilyl)trifluoroacetamide | NMR Verification |
| CAS Number | 25561-30-2 | CAS Registry |
| Molecular Formula | C8H18F3NOSi2 | Elemental Analysis |
| Purity Grade | ≥99% (GC Grade) | Gas Chromatography |
| Boiling Point | 124-126°C | ASTM E1719 |
Competitive Product Analysis
| Feature | Standard Grade | HPLC Grade | Industrial Grade |
|---|---|---|---|
| Purity Level | 99.0% | 99.9% | 97.5% |
| Moisture Content | ≤0.5% | ≤0.1% | ≤1.0% |
| Packaging | 50mL Ampoule | 100mL Sealed Vial | 1L HDPE Bottle |
BSTFA Functional Applications
Core Industrial Uses
- GC-MS Derivatization Agent for polar compounds analysis
- Pharmaceutical intermediate in API synthesis
- Siliconizing reagent for surface modification
- Polymer stabilizer in fluoropolymer production
Optimized Reaction Conditions
| Application | Recommended Ratio | Reaction Time | Temperature Range |
|---|---|---|---|
| Carboxylic Acid Derivatization | 1:2 (analyte:BSTFA) | 30-60 mins | 60-70°C |
| Amine Silylation | 1:3 (analyte:BSTFA) | 45-90 mins | 70-80°C |
BSTFA Implementation Scenarios
Analytical Chemistry Application
Challenge: Accurate quantification of trace phenolic compounds in wastewater
Solution: BSTFA derivatization enabled GC-MS detection at 0.1ppb sensitivity
Result: Achieved EPA Method 8041 compliance with RSD <5%
Pharmaceutical Synthesis
Challenge: Stabilization of heat-sensitive cephalosporin intermediates
Solution: BSTFA-mediated protection of hydroxyl groups
Result: Increased intermediate stability by 78% at 25°C
Client Success Stories
Case 1: European Pharmaceutical Manufacturer
Client Profile: Top 10 generic drug producer
Project Scope: Scale-up of antihypertensive API synthesis
BSTFA Role: Critical silylation agent in protection-deprotection sequence
Outcome: Achieved 92% yield improvement vs previous TMCS method
Case 2: US Analytical Laboratory
Client Profile: FDA-certified testing facility
Project Scope: Pesticide residue analysis in food products
BSTFA Application: Derivatization of chlorophenoxy acids
Outcome: Reduced sample prep time by 40% with 99.2% recovery rate
Technical Support & Ordering Information
Quality Assurance Protocols
- Batch-specific GC-MS certification
- ISO 9001:2015 compliant manufacturing
- Strict -20°C storage & transportation
Contact Our Experts
For technical specifications sheets or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826
Request Custom Documentation:
• Certificate of Analysis (CoA)
• Material Safety Data Sheet (MSDS)
• Stability & Compatibility Studies



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