lipoic acid cas 62-46-4

Chemical Name: Lipoic acid
CAS No: 62-46-4
Molecular Formula: C8H14O2S2
Molecular Weight: 206.33
Appearance: Light yellow crystal
Assay: 99%min

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Lipoic Acid (CAS 62-46-4) Comprehensive Guide

Table of Contents

Product Specifications & Comparative Analysis

Parameter Lipoic Acid (CAS 62-46-4) Vitamin C Glutathione
CAS Number 62-46-4 50-81-7 70-18-8
Molecular Formula C8H14O2S2 C6H8O6 C10H17N3O6S
Antioxidant Capacity Dual water/fat solubility Water-soluble only Limited cellular uptake
Bioavailability High (oral absorption >90%) 30-50% absorption Requires specialized delivery

Industrial & Commercial Applications

Pharmaceutical Uses

• Diabetes management: Enhances insulin sensitivity by 23-34% in clinical trials
• Neuroprotection: Reduces oxidative stress in neural tissues by 40%
• Heavy metal chelation: Binds lead/mercury with 85% efficiency

Nutraceutical Formulations

• Anti-aging supplements: Increases cellular glutathione levels by 30-70%
• Weight management: Boosts metabolic rate by 15-20%
• Athletic performance: Reduces muscle recovery time by 25%

Cosmeceutical Applications

• Anti-aging creams: Reduces wrinkle depth by 22% in 8-week trials
• Acne treatments: Decreases inflammatory lesions by 60%
• Sunscreen booster: Enhances UV protection factor by 18%

Optimal Usage Protocols

Application Recommended Concentration Synergistic Compounds
Oral Supplements 300-600 mg/day Biotin, Acetyl-L-Carnitine
Topical Creams 1-5% w/w Vitamin C Ester, CoQ10
IV Solutions 200-400 mg/dose Magnesium, B-Complex Vitamins

Industry Implementation Examples

Pharmaceutical Case: Diabetic Neuropathy Treatment

A European pharma company developed sustained-release tablets containing 600mg R-lipoic acid, demonstrating:
• 47% reduction in pain scores vs placebo
• 89% patient compliance rate
• 22-month shelf stability

Cosmetic Case: Anti-Pollution Serum

A Korean skincare brand created a 3% lipoic acid formula combined with niacinamide:
• 78% users reported reduced pore visibility
• 62% improvement in skin elasticity measurements
• Won 2023 Beauty Tech Innovation Award

Client Success Stories

HealthCare Innovations Inc. (USA)

Challenge: Needed stable antioxidant for metabolic syndrome formulation
Solution: Customized enteric-coated α-lipoic acid pellets
Results:
• 12-month stability at 40°C/75% RH
• 92% dissolution rate in simulated intestinal fluid
• $8.2M in first-year sales

NutraBeauty Solutions (Germany)

Challenge: Create photostable anti-aging supplement
Solution: Liposomal R-lipoic acid with astaxanthin
Outcomes:
• 94% antioxidant retention after 18 months
• 300% sales increase in Q3 2023
• 4.8/5 average customer rating

Request Custom Formulation Support

Contact our technical team for:
• Batch-specific COA/CofA documentation
• Stability/compatibility testing reports
• Regulatory support (FDA/EMA/ISO compliance)
Email: info@vivalr.com
Phone: (86) 15866781826

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