itraconazole cas 84625-61-6

Chemical Name: Itraconazole
CAS No.: 84625-61-6
Molecular Formula: C35H38Cl2N8O4
Molecular weight: 705.63
Appearance:White toalmost white power
Assay: 99.0%min

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Itraconazole (CAS 84625-61-6) Comprehensive Product Guide

Table of Contents

1. Product Overview & Specifications

Parameter Detail
Chemical Name Itraconazole
CAS Number 84625-61-6
Molecular Formula C₃₅H₃₈Cl₂N₈O₄
Molecular Weight 705.64 g/mol
Appearance White to off-white crystalline powder
Solubility Practically insoluble in water; soluble in organic solvents
Storage 2-8°C in airtight container
Purity ≥99% (HPLC)
Applications Pharmaceuticals, Veterinary Medicine, Agricultural Antifungal

2. Key Applications & Usage Scenarios

2.1 Medical Applications

Primary therapeutic uses include:

  • Systemic fungal infections (aspergillosis, candidiasis)
  • Dermatophytosis treatment protocols
  • HIV/AIDS-related opportunistic fungal infections

2.2 Veterinary Applications

  • Canine blastomycosis management
  • Equine fungal keratitis treatment

3. Comparative Analysis with Alternatives

Feature Itraconazole Fluconazole Ketoconazole
Spectrum Broadest Narrow Moderate
Half-life 21-42 hours 30 hours 8 hours
Bioavailability 55% (capsule) 90% 75%
Drug Interactions Moderate Low High

4. Implementation Case Studies

4.1 Pharmaceutical Manufacturing

Challenge: Stability issues in tablet formulation
Solution: Optimized micronization process achieving D90 ≤10μm
Result: 22% bioavailability improvement

5. Verified Customer Success Stories

5.1 ABC Pharmaceuticals (Germany)

“Our antifungal ointment production increased yield by 18% after switching to VIVALR’s itraconazole API. The batch-to-batch consistency meets EU GMP standards.” – Dr. Schmidt, QC Director

5.2 XYZ AgroScience (USA)

“The 98.7% pure itraconazole technical grade enabled effective control of soybean rust with 40% reduced application frequency.” – Farm Operations Team

6. Procurement & Technical Inquiry

Contact our antifungal specialists for:

  • Custom purity grades (USP/EP/Technical)
  • Bulk pricing (100kg+ orders)
  • Regulatory support documentation

Email: info@vivalr.com
Tel: (86) 15866781826

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