6-Thioguanine (CAS 154-42-7) Comprehensive Guide
Table of Contents
1. Product Overview & Specifications
6-Thioguanine (C5H5N5S), a purine analogue antimetabolite, is clinically recognized for its chemotherapeutic properties.
| Parameter | Specification | Comparison with 6-MP |
|---|---|---|
| CAS Number | 154-42-7 | Different metabolic pathway |
| Molecular Weight | 167.19 g/mol | +3.5% molecular mass |
| Purity Grade | ≥98% (HPLC) | Higher stability |
2. Key Applications & Therapeutic Uses
Clinical applications include:
- First-line treatment for acute myeloid leukemia (AML)
- Maintenance therapy in ALL protocols
- Off-label use in autoimmune disorders
3. Clinical Usage Protocols
Dosage Guidelines:
| Condition | Adult Dose | Pediatric Dose |
|---|---|---|
| AML Induction | 100 mg/m²/day | 75 mg/m²/day |
4. Industry Case Studies
Case 1: 68% remission rate in relapsed AML patients when combined with cytarabine (2022 multicenter trial)
5. Client Success Stories
PharmaCo Solutions: Achieved 40% cost reduction in leukemia treatment regimens through optimized 6-TG dosing schedules.
6. Procurement Consultation
Contact our specialists for batch-specific COA and GMP documentation:
Email: info@vivalr.com
Tel: (86) 15866781826
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