Nimodipine (CAS 66085-59-4) Comprehensive User Guide
Table of Contents
- 1. Product Overview & Specifications
- 2. Parameter Comparison
- 3. Key Applications & Clinical Uses
- 4. Professional Usage Guidelines
- 5. Verified Client Case Studies
- 6. Request Customized Solutions
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methoxyethyl 1-methylethyl ester |
| CAS Number | 66085-59-4 |
| Molecular Formula | C21H26N2O7 |
| Appearance | Yellow crystalline powder |
| Solubility | Practically insoluble in water, soluble in ethanol |
2. Calcium Channel Blockers Comparison
| Feature | Nimodipine | Nifedipine | Amlodipine |
|---|---|---|---|
| Cerebroselectivity | High | Low | Moderate |
| Half-life | 8-9 hours | 2-5 hours | 30-50 hours |
| Primary Indication | SAH complications | Hypertension | Chronic angina |
3. Clinical & Industrial Applications
3.1 Primary Medical Uses
- Prevention/treatment of cerebral vasospasm following subarachnoid hemorrhage (SAH)
- Neuroprotective agent in ischemic stroke
- Migraine prophylaxis (off-label use)
3.2 Research Applications
- Calcium signaling pathway studies
- Blood-brain barrier permeability research
- Neurovascular coupling investigations
4. Professional Usage Protocol
4.1 Recommended Dosage
| Administration | Dosage | Frequency |
|---|---|---|
| Oral | 60mg | Every 4 hours |
| IV Infusion | 1-2 mg/hr | Continuous |
4.2 Critical Handling Notes
- Protect from light exposure during storage
- Use glass containers for IV solutions
- Monitor blood pressure during administration
5. Verified Client Implementations
5.1 Hospital Neurology Department Case
Client: Tertiary Care Hospital in Germany (2019-2022)
Application: SAH complication management
Results: 42% reduction in delayed cerebral ischemia
5.2 Pharmaceutical Manufacturer Experience
Client: EU-based Generic Producer
Application: Tablet formulation development
Outcome: Achieved 98.7% purity in final product
6. Request Customized Solutions
Contact our technical specialists for:
- Bulk pharmaceutical-grade supply
- Custom formulation development
- Clinical trial material support
Email: info@vivalr.com
Phone: (86) 15866781826
相关产品
Chemical Name: Eicosatetraynoic acid(ETYA)
Cas No.: 1191-85-1
Molecular Fomula: C20H24O2
Molecular Weight: 296.4
Chemical Name: Choline salicylate
CAS No.: 2016-36-6
Molecular Formula: C12H19NO4
Molecular Weight: 241.28
Appearance: Red-Brown Crystal
Chemical Name: o-Xylene
Synonyms: 1,2-Dimethylbenzene; ortho-xylene
CAS No.: 95-47-6
Molecular Formula: C8H10
Molecular Weight: 106.17
Chemical Name: 1-[9-ethyl-6-(4-fluoro-benzoyl)-9H-carbazol-3-yl]-ethanone
Cas No.: 876907-97-0
Molecular Fomula: C23H18FNO2
Molecular Weight: 359.39
Chemical Name: 1-Hexadecylamine
Synonyms 1-Aminohexadecane; Hexyldecylamine; n-Certylamine
CAS No.: 143-27-1
Molecular Formula: C16H35N
Molecular Weight: 241.46
Appearance: White Crystal
Chemical Name: 1,5-Diphenylcarbazide
Synonyms: 1,5-Diphenylcarbohydrazide; 2,2’-diphenylcarbazide; Diphenylcartazide; sym-diphenylcarbazide
CAS No.: 140-22-7
Molecular Formula: C13H14N4O
Molecular Weight: 242.28
Chemical Name: D-PANTOTHENIC ACID
CAS No.: 79-83-4
Molecular Formula: C9H17NO5
Molecular Weight: 219.24
Appearance: Colorless or Light Yellow Oily Liquid
Chemical Name: DL-4-Chlorophenylglycine
Cas No.: 6212-33-5
Molecular Fomula: C8H8ClNO2
Molecular Weight: 185.61
Chemical Name: Oxirane, methyl-, polymer with oxirane, dodecyl ether
Cas No.: 68238-81-3
Molecular Fomula: C17H36O3
Molecular Weight: 288.46594
Chemical Name: D-PANTOTHENIC ACID
CAS No.: 79-83-4
Molecular Formula: C9H17NO5
Molecular Weight: 219.24
Appearance: Colorless or Light Yellow Oily Liquid
Chemical Name: STODDARD SOLVENT
CAS No.: 64742-88-7
Appearance: Colorless or Light Yellow Liquid
Chemical Name: Tribehenin
Cas No.: 18641-57-1
Molecular Fomula: C69H134O6
Molecular Weight: 1059.8
Appearance: White waxy powder or solid
评论
目前还没有评论。