Nimodipine (CAS 66085-59-4) Comprehensive User Guide
Table of Contents
- 1. Product Overview & Specifications
- 2. Parameter Comparison
- 3. Key Applications & Clinical Uses
- 4. Professional Usage Guidelines
- 5. Verified Client Case Studies
- 6. Request Customized Solutions
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methoxyethyl 1-methylethyl ester |
| CAS Number | 66085-59-4 |
| Molecular Formula | C21H26N2O7 |
| Appearance | Yellow crystalline powder |
| Solubility | Practically insoluble in water, soluble in ethanol |
2. Calcium Channel Blockers Comparison
| Feature | Nimodipine | Nifedipine | Amlodipine |
|---|---|---|---|
| Cerebroselectivity | High | Low | Moderate |
| Half-life | 8-9 hours | 2-5 hours | 30-50 hours |
| Primary Indication | SAH complications | Hypertension | Chronic angina |
3. Clinical & Industrial Applications
3.1 Primary Medical Uses
- Prevention/treatment of cerebral vasospasm following subarachnoid hemorrhage (SAH)
- Neuroprotective agent in ischemic stroke
- Migraine prophylaxis (off-label use)
3.2 Research Applications
- Calcium signaling pathway studies
- Blood-brain barrier permeability research
- Neurovascular coupling investigations
4. Professional Usage Protocol
4.1 Recommended Dosage
| Administration | Dosage | Frequency |
|---|---|---|
| Oral | 60mg | Every 4 hours |
| IV Infusion | 1-2 mg/hr | Continuous |
4.2 Critical Handling Notes
- Protect from light exposure during storage
- Use glass containers for IV solutions
- Monitor blood pressure during administration
5. Verified Client Implementations
5.1 Hospital Neurology Department Case
Client: Tertiary Care Hospital in Germany (2019-2022)
Application: SAH complication management
Results: 42% reduction in delayed cerebral ischemia
5.2 Pharmaceutical Manufacturer Experience
Client: EU-based Generic Producer
Application: Tablet formulation development
Outcome: Achieved 98.7% purity in final product
6. Request Customized Solutions
Contact our technical specialists for:
- Bulk pharmaceutical-grade supply
- Custom formulation development
- Clinical trial material support
Email: info@vivalr.com
Phone: (86) 15866781826
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