Table of Contents
- 1. 2,6-Pyridinedicarboxylic Acid (CAS 499-83-2) Overview
- 2. Technical Specifications & Supplier Comparison
- 3. Industrial Applications & Functional Mechanisms
- 4. Operational Protocols & Safety Guidelines
- 5. Implementation Case Studies
- 6. Technical Consultation & Custom Synthesis Inquiry
1. 2,6-Pyridinedicarboxylic Acid (CAS 499-83-2) Overview
Molecular Formula: C7H5NO4
Molecular Weight: 167.12 g/mol
Appearance: White to off-white crystalline powder
Purity: ≥98% (HPLC)
Storage Conditions: 2-8°C in inert atmosphere
2. Technical Specifications & Supplier Comparison
| Parameter | TCI Chemicals | Sigma-Aldrich | Alfa Chemistry |
|---|---|---|---|
| Purity Grade | Reagent Grade (98%) | Pharmaceutical Secondary Standard (99.5%) | Research Grade (97%) |
| Packaging | 1g-25kg options | 5mg-10kg scale | 100mg-5kg available |
| Documentation | CoA/MSDS | GMP-compliant DMF | Technical Data Sheet |
3. Industrial Applications & Functional Mechanisms
Pharmaceutical Intermediates:
– Key precursor for kinase inhibitor APIs
– Chelating agent in metal-based therapeutics
Coordination Chemistry:
– Ligand for transition metal complexes (Fe³⁺, Cu²⁺)
– MOF (Metal-Organic Framework) construction
Polymer Science:
– Monomer for heat-resistant polyamides
– Crosslinking agent in epoxy resins
4. Operational Protocols & Safety Guidelines
Handling Procedures:
1. Use nitrogen-purged environment for weighing
2. Employ acid-resistant PPE (neoprene gloves, face shield)
Reaction Conditions:
– Optimal esterification: 140-160°C under Dean-Stark trap
– Metal complexation pH range: 4.5-6.2
Waste Management:
– Neutralize with 10% sodium bicarbonate before disposal
5. Implementation Case Studies
Case 1: Oncology Drug Development (2023)
Client: Shanghai InnovPharma Co., Ltd.
– Application: PD-1/PD-L1 inhibitor intermediate synthesis
– Outcome: 23% yield improvement vs traditional routes
– Scale: 120kg batch production validated
Case 2: Advanced Battery Materials (2024)
Client: Shenzhen PowerEner Tech
– Application: Lithium-ion battery electrolyte additive
– Result: 15% cycle life enhancement at 4.5V operation
– Certification: Passed UN38.3 safety testing
6. Technical Consultation & Custom Synthesis Inquiry
Contact our coordination chemistry specialists:
Email: info@vivalr.com
Phone: (86) 15866781826
Submit your requirements for:
– Custom purity specifications (98-99.9%)
– Isotope-labeled derivatives (¹³C, ²H)
– Bulk quantities (100kg+ GMP manufacturing)



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