2,6-pyridinedicarboxylic acid cas 499-83-2

Product Name: 2,6-Pyridinedicarboxylic acid
CAS: 499-83-2
Molecular Formula:C7H5NO4
Molecular weight:167.12
Appearance: Off-white powder
Content: ≥99%

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Table of Contents

1. 2,6-Pyridinedicarboxylic Acid (CAS 499-83-2) Overview

Molecular Formula: C7H5NO4
Molecular Weight: 167.12 g/mol
Appearance: White to off-white crystalline powder
Purity: ≥98% (HPLC)
Storage Conditions: 2-8°C in inert atmosphere

2. Technical Specifications & Supplier Comparison

Parameter TCI Chemicals Sigma-Aldrich Alfa Chemistry
Purity Grade Reagent Grade (98%) Pharmaceutical Secondary Standard (99.5%) Research Grade (97%)
Packaging 1g-25kg options 5mg-10kg scale 100mg-5kg available
Documentation CoA/MSDS GMP-compliant DMF Technical Data Sheet

3. Industrial Applications & Functional Mechanisms

Pharmaceutical Intermediates:
– Key precursor for kinase inhibitor APIs
– Chelating agent in metal-based therapeutics
Coordination Chemistry:
– Ligand for transition metal complexes (Fe³⁺, Cu²⁺)
– MOF (Metal-Organic Framework) construction
Polymer Science:
– Monomer for heat-resistant polyamides
– Crosslinking agent in epoxy resins

4. Operational Protocols & Safety Guidelines

Handling Procedures:
1. Use nitrogen-purged environment for weighing
2. Employ acid-resistant PPE (neoprene gloves, face shield)
Reaction Conditions:
– Optimal esterification: 140-160°C under Dean-Stark trap
– Metal complexation pH range: 4.5-6.2
Waste Management:
– Neutralize with 10% sodium bicarbonate before disposal

5. Implementation Case Studies

Case 1: Oncology Drug Development (2023)
Client: Shanghai InnovPharma Co., Ltd.
– Application: PD-1/PD-L1 inhibitor intermediate synthesis
– Outcome: 23% yield improvement vs traditional routes
– Scale: 120kg batch production validated

Case 2: Advanced Battery Materials (2024)
Client: Shenzhen PowerEner Tech
– Application: Lithium-ion battery electrolyte additive
– Result: 15% cycle life enhancement at 4.5V operation
– Certification: Passed UN38.3 safety testing

6. Technical Consultation & Custom Synthesis Inquiry

Contact our coordination chemistry specialists:
Email: info@vivalr.com
Phone: (86) 15866781826
Submit your requirements for:
– Custom purity specifications (98-99.9%)
– Isotope-labeled derivatives (¹³C, ²H)
– Bulk quantities (100kg+ GMP manufacturing)

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