(Trifluoromethyl)trimethylsilane (CAS 81290-20-2) Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Chemical Name: (Trifluoromethyl)trimethylsilane
CAS Number: 81290-20-2
Molecular Formula: C4H9F3Si
Molecular Weight: 154.19 g/mol
Key Parameters Comparison
| Parameter | (Trifluoromethyl)trimethylsilane | Similar Reagent A | Similar Reagent B |
|---|---|---|---|
| Purity | ≥98% | ≥95% | ≥97% |
| Boiling Point | 80-82°C | 75-78°C | 85-88°C |
2. Key Applications & Use Cases
2.1 Pharmaceutical Synthesis
Widely used as a trifluoromethylating agent in nucleophilic reactions for antiviral drug intermediates.
2.2 Material Science
Critical in synthesizing fluorinated surfactants and liquid crystal materials.
2.3 Reaction Example
Reaction with aldehydes: RCHO + CF3TMS → RCH(OH)CF3
3. Industry Case Studies
Case 1: PharmaSynth Co., Ltd.
Challenge: Low yield in trifluoromethylation of pyridine derivatives.
Solution: Optimized reaction using 1.2 eq. (Trifluoromethyl)trimethylsilane at -20°C.
Result: Yield increased from 45% to 82%.
Case 2: FluoroMaterials Inc.
Application: Production of fluorinated OLED materials.
Outcome: Achieved 99.5% purity in final product with consistent batch quality.
4. Technical Support & Inquiry
For bulk orders or technical specifications:
Email: info@vivalr.com
Tel: (86) 15866781826
Key Advantages:
- Strict QC with GC/HPLC analysis
- Custom packaging solutions
- 24/7 technical support
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