5-chloro-2,3-difluoropyridine cas 89402-43-7

Chemical Name:5-Chloro-2,3-difluoropyridine
CAS No.: 89402-43-7
Molecular Formula: C5H2ClF2N
Molecular Weight:149.53
Appearance:Colorless transparent liquid

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Guide to 5-Chloro-2,3-Difluoropyridine (CAS 89402-43-7)

Table of Contents

1. Product Overview & Specifications

Parameter Specification
CAS Number 89402-43-7
Chemical Formula C5H2ClF2N
Molecular Weight 149.53 g/mol
Appearance White to off-white crystalline powder
Purity ≥98% (HPLC)
Melting Point 45-48°C
Boiling Point 205-208°C
Storage Conditions 2-8°C in inert atmosphere

2. Parameter Comparison

Vendor Purity Packaging Price/kg
Supplier A 98% 1kg foil bag $1,200
Supplier B 99% 5kg drum $1,050
Vivalr Solutions 99.5% Custom packaging $980

3. Key Applications

Pharmaceutical Intermediates

Critical component in synthesis of:

  • Antiviral medications
  • Kinase inhibitors
  • Neuroprotective agents

Agrochemical Formulations

  • Herbicide precursors
  • Fungicide active ingredients

Advanced Material Synthesis

  • Liquid crystal materials
  • OLED precursors

4. Usage Guidelines

Handling Recommendations

  • Use nitrogen glove boxes for moisture-sensitive reactions
  • Maintain pH between 6.5-7.5 in aqueous systems

Reaction Optimization

Reaction Type Optimal Temperature Catalyst Compatibility
Buchwald-Hartwig 110-120°C Pd(OAc)2/XPhos
Suzuki Coupling 80-90°C Pd(PPh3)4

5. Industry Case Studies

Case Study 1: Antiviral Drug Development

Client: European Pharma Research Group
Application: Nucleoside analog synthesis
Result: Achieved 92% yield in key coupling reaction

Case Study 2: Crop Protection Formulation

Client: Asian Agrochemical Manufacturer
Application: Systemic fungicide development
Result: 40% improvement in fungal resistance

6. Client Implementation Examples

Pharmaceutical Manufacturer (Germany)

  • Annual consumption: 850kg
  • Used in Phase III clinical trial material
  • Purity requirement: 99.9%

Electronic Materials Supplier (USA)

  • Application: Organic semiconductor synthesis
  • Batch consistency: RSD <0.5%
  • Custom particle size distribution

7. Contact for Technical Consultation

For formulation support or bulk pricing:
Email: info@vivalr.com
Phone: (86) 15866781826

Request free sample analysis:
[Submit technical requirements for customized quotation]

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