4-Pyrimidinamine, 5-(Bromomethyl)-2-methyl-, Monohydrobromide Cas 2908-71-6

Chemical Name: 4-Pyrimidinamine, 5-(bromomethyl)-2-methyl-, monohydrobromide
CAS No.:  2908-71-6
Molecular Fomula: C6H9Br2N3
Molecular weight: 282.96400
Appearance: White crystalline powder
Assay:≥98.0%

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4-Pyrimidinamine, 5-(Bromomethyl)-2-methyl-, Monohydrobromide (CAS 2908-71-6) Product Guide

1. Product Specifications & Comparative Analysis

Parameter Specification Alternative Compound
CAS Number 2908-71-6 528878-44-6 (Analog)
Molecular Formula C6H8Br2N3 C5H8Br2N2
Molecular Weight 275.96 g/mol 255.94 g/mol
Purity Grade Pharmaceutical (≥98%) Industrial (≥95%)

2. Functional Applications

This brominated pyrimidine derivative serves as:

  • Key intermediate in kinase inhibitor synthesis
  • Building block for anticancer drug candidates
  • Cross-linking agent in polymer chemistry
  • Precursor for radiopharmaceutical labeling

3. Operational Protocols

Storage: Maintain at 2-8°C under inert atmosphere

Handling: Use PPE including nitrile gloves and chemical goggles

Solubility: 25 mg/mL in DMSO (clear solution at 20°C)

4. Industry Case Studies

Case A: Used in Phase II clinical trial material synthesis for non-small cell lung cancer treatment (2024)

Case B: Enabled 32% yield improvement in antiviral compound production through optimized bromination (2023)

5. Client Success Stories

PharmaCorp Inc. (USA):

  • Application: EGFR inhibitor development
  • Quantity: 15 kg batch order
  • Result: Achieved 99.2% HPLC purity

BioResearch GmbH (Germany):

  • Application: Radioligand synthesis
  • Quantity: 500g custom synthesis
  • Result: Successful 18F labeling efficiency (82%)

6. Technical Consultation & Quotation

Request custom synthesis quotes or technical documents:

Email: info@vivalr.com

Phone: (86) 15866781826

Provide:

  • Required quantity
  • Purity specifications
  • Application context
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