Comprehensive Guide to Isonicotinic Acid
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Industry Uses
- 3. Performance Comparison with Alternatives
- 4. Operational Guidelines & Safety Protocols
- 5. Real-World Implementation Case Studies
- 6. Custom Solutions & Commercial Inquiry
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | Isonicotinic Acid (4-Pyridinecarboxylic Acid) |
| CAS Number | 55-22-1 |
| Molecular Formula | C6H5NO2 |
| Appearance | White to off-white crystalline powder |
| Purity Grade | Pharmaceutical (≥99.5%)/Industrial (≥98%) |
| Melting Point | 310-315°C (dec.) |
| Solubility | Soluble in hot water, ethanol, and alkaline solutions |
| Storage | 2-8°C in airtight container |
2. Key Applications & Industry Uses
Pharmaceutical Manufacturing
Primary intermediate for anti-tuberculosis drugs including isoniazid (INH), pyrazinamide, and ethionamide.
Agrochemical Production
Key component in synthesis of neonicotinoid insecticides such as imidacloprid.
Chemical Research
Building block for coordination polymers and metal-organic frameworks (MOFs).
3. Performance Comparison with Alternatives
| Feature | Isonicotinic Acid | Nicotinic Acid | Picolinic Acid |
|---|---|---|---|
| Positional Isomer | 4-pyridine | 3-pyridine | 2-pyridine |
| Pharma Applications | Anti-TB drugs | Vitamin B3 | Herbicides |
| Reactivity | High | Medium | Low |
4. Operational Guidelines & Safety Protocols
Handling Requirements
- PPE: Nitrile gloves, chemical goggles, lab coat
- Ventilation: Use fume hood for powder handling
Storage Conditions
- Separate from strong oxidizers and bases
- Maintain humidity below 60% RH
5. Real-World Implementation Case Studies
Case 1: Antitubercular Drug Production
Client: Leading Indian Pharma Manufacturer
Usage: 12 MT/year for isoniazid API production
Result: Achieved 99.8% purity meeting USP 43 standards
Case 2: Advanced Material Synthesis
Client: German Chemical Research Institute
Application: MOF development for gas storage
Outcome: Created novel adsorbent with 20% higher CO2 capacity
6. Custom Solutions & Commercial Inquiry
Why Choose Us?
- GMP-certified production facilities
- Bulk quantities up to 50 MT/month capacity
- Global logistics support with DDP terms
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Technical Support
Available MSDS, COA, and synthesis protocol guidance
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