6-Iodo-1H-indazole

Table of Contents

• Product Overview & Specifications
• Applications & Industrial Uses
• Case Studies
• Client Success Stories
• Contact for Custom Solutions

Product Overview & Specifications

6-Iodo-1H-indazole

CAS Number: 261953-36-0

Molecular Formula: C₇H₅IN₂

Molecular Weight: 260.03 g/mol

Purity: ≥95% (HPLC)

Comparative Specifications

Applications & Industrial Uses

Pharmaceutical Intermediates

Widely used in synthesizing kinase inhibitors and anticancer agents due to its halogen-substituted indazole core, enabling selective binding to biological targets.

Organic Synthesis

Serves as a precursor for cross-coupling reactions (e.g., Suzuki-Miyaura) to construct complex heterocycles like 3-thiopheneboronic acid derivatives.

Agrochemical Research

Key intermediate in developing crop protection agents, leveraging its stability and reactivity under industrial conditions.

Case Studies

Case 1: Antiviral Drug Development

A European pharmaceutical company utilized 6-Iodo-1H-indazole to synthesize novel protease inhibitors, achieving 78% yield in optimized Buchwald-Hartwig amination.

Case 2: OLED Material Innovation

Japanese researchers incorporated iodinated indazole derivatives into electron-transport layers, enhancing device efficiency by 22% compared to conventional materials.

Client Success Stories

Shanghai Yuanye Bio-Tech

Procured 25kg batch for continuous flow chemistry trials, reducing reaction times from 18 hours to 3.5 hours in API manufacturing.

Shenzhen Highsain Biotech

Integrated 6-Iodo-1H-indazole into high-throughput screening libraries, identifying two lead compounds with nanomolar IC₅₀ values against solid tumors.

Contact for Custom Solutions

Email: info@vivalr.com

Phone: (86) 15866781826

Request tailored synthesis protocols, bulk pricing, or technical documentation via our 24/7 inquiry portal.