2-Hydroxy-4-quinolincarboxylic acid

1. Product Overview & Specifications

2-Hydroxy-4-quinolincarboxylic acid (CAS: 15733-89-8) is a quinoline derivative with the molecular formula C₁₀H₇NO₃ and a molecular weight of 189.17 g/mol. It is supplied as a yellow crystalline powder with a purity of ≥98.0% (HPLC).

2. Key Applications

This compound is primarily utilized in:

• Pharmaceutical Intermediates: Synthesis of antimicrobial and antimalarial agents.
• Coordination Chemistry: Chelating agent for metal ions in analytical chemistry.
• Material Science: Precursor for functionalized polymers and coatings.

3. Usage Guidelines

Handling Precautions:

• Store in a cool, dry environment (2–8°C) under inert gas (e.g., nitrogen).
• Use personal protective equipment (gloves, goggles) to avoid inhalation or skin contact.

Reaction Optimization:

• For carboxylation reactions, maintain pH 6–8 in aqueous solutions.
• Compatible with palladium catalysts for cross-coupling applications.

4. Client Case Studies

Case Study 1: Pharmaceutical Manufacturer (Shanghai, China)

• Objective: Develop a novel quinolone antibiotic.
• Outcome: Achieved 92% yield in the key intermediate synthesis using 2-Hydroxy-4-quinolincarboxylic acid.

Case Study 2: Analytical Laboratory (Berlin, Germany)

• Objective: Detect trace copper ions in industrial wastewater.
• Outcome: Successfully quantified Cu²⁺ at 0.1 ppm levels via chelation-based spectrophotometry.

5. Contact for Technical Support

For bulk orders, custom synthesis, or technical queries: