Table of Contents
8-Nitroquinoline: Technical Profile
CAS No.: 607-35-2
Molecular Formula: C9H6N2O2
Molecular Weight: 174.16 g/mol
Appearance: Pale yellow crystalline solid
Key Physicochemical Properties
| Parameter | Value |
|---|---|
| Melting Point | 89-91°C |
| Boiling Point | 323.1°C at 760 mmHg |
| Density | 1.219 g/cm³ |
| LogP | 2.67 |
| Purity Grade | Analytical Reagent (≥97%-98%) |
Specification Comparison
| Vendor | Purity | Packaging | Regulatory Status |
|---|---|---|---|
| Supplier A | ≥97% | 25g-500g | Non-hazardous |
| Supplier B | ≥98% | 100g-1kg | Xn Classification |
Core Industrial Applications
Pharmaceutical Manufacturing
Critical intermediate in synthesis of antimalarial agents and antibacterial compounds
Agrochemical Production
Key precursor for nitro-substituted quinoline pesticides with enhanced bioactivity
Chemical Research
Building block for developing novel heterocyclic compounds in material science
Pharmaceutical Intermediate Case Study
Challenge: Required high-purity intermediate for antituberculosis drug R&D
Solution: Implemented 98% pure 8-Nitroquinoline in multi-step synthesis
Outcome: Achieved 92% yield in final API synthesis with reduced impurities
Agrochemical Synthesis Case Study
Challenge: Developing next-generation fungicidal compounds
Application: Used as nitration precursor in quinoline-based fungicide development
Result: 40% improvement in compound stability vs traditional derivatives
Client Implementations
Guangdong Wengjiang Chemical
Utilized 500kg batches for API intermediate production since 2022
Wuhan WinYuanBei Commerce
Integrated into specialty chemical formulations for export markets
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