1. Product Overview & Specifications

(R)-(-)-2-Methylpiperazine (CAS 75336-64-6) is a chiral piperazine derivative with molecular formula C₅H₁₂N₂. Key parameters:

2. Key Applications & Industrial Uses

Pharmaceutical Intermediate

Critical component in synthesis of:

• Atypical antipsychotics (e.g., Aripiprazole derivatives)
• Antidepressant APIs
• Kinase inhibitors

Chemical Synthesis

• Chiral catalyst preparation
• Ligand development for asymmetric catalysis

3. Operational Best Practices

Storage Guidelines

• Maintain at 2-8°C in inert atmosphere
• Desiccate immediately after opening

Reaction Optimization

• Optimal pH range: 7.8-8.5
• Recommended solvent systems: THF/DMF mixtures

4. Implementation Case Studies

Case 1: Anticancer Drug Synthesis

Challenge: Achieve >98% enantiomeric excess in kinase inhibitor precursor
Solution: Implemented our 99% ee grade material with modified Buchwald-Hartwig conditions
Result: 99.2% final API purity, 23% yield improvement

5. Client Success Stories

PharmaCorp Solutions (Top-10 Global Pharma)

Challenge: Scale-up issues in antipsychotic production
Solution: Custom particle size distribution batch (D90 < 50μm)
Outcome: 40% reduction in reaction time, validated 5,000L batches

Advanced ChemTech (CDMO)

Challenge: Regulatory compliance for US/EU markets
Solution: Full ICH-compliant documentation package
Outcome: Successful FDA/EMA filings, 100% audit success rate

6. Contact Our Experts

Request technical documentation or discuss custom synthesis requirements:

Email: info@vivalr.com
Phone: (86) 15866781826

Available 24/7 for emergency pharmaceutical supply chain support