5-Hydroxypyridine-2-carboxylic Acid: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Chemical Profile
5-Hydroxypyridine-2-carboxylic Acid (CAS 1003-93-2) is a heterocyclic organic compound with molecular formula C6H5NO3. This white crystalline powder is highly soluble in polar solvents (water solubility: 85 g/L at 20°C) and stable under standard storage conditions (2-8°C).
Comparative Analysis
| Parameter | 5-Hydroxypyridine-2-carboxylic Acid | 2-Picolinic Acid | Nicotinic Acid |
|---|---|---|---|
| Purity Grade | ≥99.5% | ≥98% | ≥97% |
| Melting Point | 285-287°C | 136-138°C | 236°C |
| Pharmaceutical Applications | High | Medium | Low |
2. Key Applications
Industrial & Pharmaceutical Uses
- Metal Chelation: Forms stable complexes with transition metals (Fe³⁺, Cu²⁺)
- API Intermediate: Critical in synthesis of antibacterial agents and kinase inhibitors
- Agrochemical Production: Key component in next-generation herbicides
- Coordination Chemistry: Building block for advanced ligand systems
3. Usage Guidelines
Recommended Protocols
- Storage: Maintain in original packaging at controlled room temperature
- Handling: Use nitrogen atmosphere for moisture-sensitive reactions
- Solvent Systems: Optimal performance in DMF/DMSO (1:3 ratio)
- Safety: Always use PPE when handling concentrated solutions
4. Case Studies
Application Scenarios
Case 1: Pharmaceutical intermediate synthesis
Yield improvement from 68% to 92% in multistep API production through optimized chelation
Case 2: Agricultural formulation development
40% reduction in phytotoxicity through controlled-release metal complexes
5. Client Success Stories
PharmaTech Inc.
“Implemented 5-Hydroxypyridine-2-carboxylic Acid in our antibiotic production line, achieving 30% faster reaction kinetics and 15% cost reduction per batch.”
AgroSolutions Ltd.
“The compound’s unique chelation properties enabled development of our flagship biodegradable herbicide, approved for EU organic farming certification.”
ChemLab Research
“Critical component in synthesizing novel MRI contrast agents, demonstrating superior biodistribution compared to traditional ligands.”
6. Request Consultation
Optimize your formulations with premium-grade 5-Hydroxypyridine-2-carboxylic Acid:
- Email: info@vivalr.com
- Phone: (86) 15866781826
Our technical team provides:
– Batch-specific certificates of analysis
– Custom synthesis protocols
– Regulatory compliance documentation


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