4-Amino-3-chloropyridine

Product Name:4-Amino-3-chloropyridine
CAS:19798-77-7
MFC5H5ClN2
MW:128.56
EINECS:
MOL File:19798-77-7.mol

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4-Amino-3-chloropyridine: Comprehensive Product Guide

Table of Contents

1. Product Overview & Specifications

CAS Number: 7358-44-5

Molecular Formula: C5H5ClN2

Molecular Weight: 128.56 g/mol

Appearance: White to off-white crystalline powder

Purity: ≥98% (HPLC)

Storage: 2-8°C in airtight container

2. Key Applications & Industry Uses

Pharmaceutical Intermediates

Critical for synthesizing kinase inhibitors and anticancer agents.

Agrochemical Production

Used in novel pesticide formulations targeting resistant crop pathogens.

Material Science

Building block for coordination polymers with luminescent properties.

3. Performance Comparison with Similar Compounds

Parameter 4-Amino-3-chloropyridine 2-Amino-3-chloropyridine 4-Amino-2-chloropyridine
Melting Point 142-145°C 138-140°C 155-158°C
Solubility in Water Slightly soluble Moderate Poor
Reactivity High Medium Low

4. Usage Scenarios & Best Practices

Drug Synthesis Protocol

Optimal reaction conditions: 0.1M concentration in DMF at 80°C under nitrogen.

Catalyst Integration

Combine with Pd(PPh3)4 for Suzuki coupling reactions (yield >85%).

5. Verified Customer Case Studies

Case 1: PharmaCorp Ltd. (Germany)

Application: Bruton’s tyrosine kinase (BTK) inhibitor development

Result: Achieved 92% yield in key intermediate synthesis

Case 2: AgroSolutions Co. (USA)

Application: Systemic insecticide for cotton crops

Result: 40% improvement in pest resistance management

Case 3: PolymerTech Inc. (Japan)

Application: Conductive polymer for flexible electronics

Result: Achieved 10-3 S/cm conductivity

6. Request Customized Solutions

Contact our technical team for bulk pricing and synthesis optimization support:

Email: info@vivalr.com

Phone: (86) 15866781826

Available services:

  • Custom purity levels (98%-99.9%)
  • GMP-grade production
  • Technical documentation support
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