2-(Trifluoromethyl)pyridine

Product Name:2-(Trifluoromethyl)pyridine
CAS:368-48-9
MFC6H4F3N
MW:147.1
EINECS:626-032-0
MOL File:368-48-9.mol

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2-(Trifluoromethyl)pyridine: Comprehensive User Guide

1. Product Overview & Specifications

2-(Trifluoromethyl)pyridine (CAS 349-43-1) is a fluorinated heterocyclic compound with molecular formula C6H4F3N. Key parameters:

Parameter Specification Competitor A Competitor B
Purity ≥99.5% ≥98% ≥99%
Boiling Point 142-144°C 138-142°C 140-143°C
Storage Temp 2-8°C Ambient 0-5°C

2. Key Applications

  • Pharmaceutical Intermediate: Synthesis of kinase inhibitors and antiviral agents
  • Agrochemical Production: Building block for novel pesticides
  • Material Science: Fluorinated liquid crystals for displays
  • Coordination Chemistry: Ligand for transition metal complexes

3. Usage Guidelines

  1. Handle under inert atmosphere (N2 or Ar) for moisture-sensitive reactions
  2. Recommended solvent systems: THF/DMF (1:3) at 60-80°C
  3. Maximize yield in Suzuki couplings using Pd(PPh3)4 catalyst
  4. Store in amber glass containers with PTFE-lined caps

4. Industry Case Studies

Case 1: Antiviral Drug Development

A Top-10 Pharma company achieved 92% yield in nucleoside analog synthesis using our 2-(Trifluoromethyl)pyridine as key intermediate, accelerating their COVID-19 therapeutic program.

Case 2: OLED Manufacturing

Display manufacturer reduced pixel response time by 40% through incorporation of our fluorinated pyridine derivatives in electron transport layers.

5. Client Success Stories

ABC Pharmaceuticals (Frankfurt, Germany)

“Consistent ≥99.5% purity enabled us to meet strict EMA guidelines for our JAK inhibitor pipeline. Batch-to-batch variability reduced by 70% compared to previous suppliers.”

AgroChem Solutions Ltd. (Mumbai, India)

“Custom bulk packaging and just-in-time delivery supported our neonicotinoid replacement program, achieving 35% cost reduction in formulation development.”

6. Contact for Custom Solutions

Request technical documentation or discuss project-specific requirements:

info@vivalr.com
(86) 15866781826

Why Choose Us?

  • ISO 9001-certified production
  • Custom synthesis up to 100kg scale
  • 24/7 technical support

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