2-(Trifluoromethyl)nicotinic acid

Product Name:2-(Trifluoromethyl)nicotinic acid
CAS:131747-43-8
MFC7H4F3NO2
MW:191.11
EINECS:223-090-5
MOL File:131747-43-8.mol

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2-(Trifluoromethyl)nicotinic Acid: Comprehensive Product Guide

Contents

1. Product Overview & Specifications

Parameter Specification Competitor A Competitor B
CAS Number 131747-57-8 131747-57-8 131747-57-8
Molecular Formula C7H4F3NO2 Same Same
Purity ≥98% (HPLC) ≥95% ≥97%
Melting Point 148-152°C 145-150°C 147-151°C

2. Key Applications

Pharmaceutical Intermediate: Critical building block for kinase inhibitors and antiviral agents.

Agrochemicals: Used in synthesizing herbicides with enhanced leaf permeability due to trifluoromethyl group.

Material Science: Precursor for fluorinated liquid crystals in advanced display technologies.

3. Usage Guidelines

Storage: Keep at 2-8°C in airtight container under inert gas. Shelf life: 24 months.

Handling: Use PPE (nitrile gloves, safety goggles) due to potential irritant properties.

Solubility: Soluble in DMF (50 mg/ml), DMSO (30 mg/ml), methanol (15 mg/ml).

4. Case Studies

Case 1: Oncology Drug Development

Client: European Pharma Co.

Challenge: Required high-purity trifluoromethylated intermediate for Phase II clinical trial material.

Solution: Supplied 98.7% HPLC-grade material with full analytical documentation (COA, MSDS, NMR).

Outcome: Successful synthesis of EGFR inhibitor candidate, 20% yield improvement over previous supplier.

Case 2: Next-Gen Herbicide Formulation

Client: US Agrochemical Manufacturer

Challenge: Needed cost-effective synthesis route for field trial quantities (50kg).

Solution: Custom synthesis with 99% purity at 40% lower cost than market average.

Outcome: Achieved EPA approval for new pre-emergence herbicide with 15% higher efficacy.

5. Inquiry & Contact

Why Choose Us?

  • ISO 9001-certified production
  • Bulk quantities (up to 500kg/month)
  • Custom synthesis & derivatization services

Email: info@vivalr.com
Phone: (86) 15866781826

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