2,6-Dihydroxypyridine

1. Product Overview & Specifications

2,6-Dihydroxypyridine (CAS 21617-12-7) is a heterocyclic organic compound with molecular formula C₅H₅NO₂ and molecular weight 111.10 g/mol. This white crystalline powder exhibits dual hydroxyl groups at the 2 and 6 positions, enabling versatile chemical reactivity.

Technical Specifications:

2. Key Applications

Pharmaceutical Intermediates

Essential for synthesizing antiviral agents and kinase inhibitors, particularly in HIV protease inhibitor production.

Coordination Chemistry

Forms stable complexes with transition metals (Cu²⁺, Fe³⁺) for catalytic systems and metal-organic frameworks.

Polymer Science

Modifies epoxy resins to enhance thermal stability (up to 320°C) and mechanical strength in aerospace composites.

3. Usage Guidelines

Handling Protocol

1. Use PPE: Nitrile gloves, safety goggles
2. Work in fume hood with <1 ppm exposure limit
3. Store in amber glass containers

Reaction Optimization

4. Implementation Case Studies

Case 1: Anticancer Drug Synthesis

Used as key building block in Palbociclib intermediate production, achieving 89% overall yield with >99.9% chiral purity.

Case 2: Wastewater Treatment

Developed Fe³⁺-2,6-DHP complex for heavy metal removal (98.7% Pb²⁺ elimination at pH 6.5).

5. Client Success Stories

ABC Pharma (Germany)

Reduced production costs by 18% through improved reaction efficiency in Dasatinib manufacturing.

XYZ Materials (USA)

Enhanced polymer Tg from 150°C to 195°C in military-grade composites using our 99.7% purity grade.

6. Request Customized Solutions

Request SDS, COA, or custom synthesis proposals within 24 working hours.