2-ACETYL-5-CHLOROTHIOPHENE

Product Name:2-ACETYL-5-CHLOROTHIOPHENE
CAS:6310-09-4
MFC6H5ClOS
MW:160.62
EINECS:228-630-3
MOL File:6310-09-4.mol

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2-Acetyl-5-Chlorothiophene: Comprehensive User Guide

1. Product Overview & Specifications

2-Acetyl-5-Chlorothiophene (CAS: 6310-09-4) is an organosulfur compound with the molecular formula C6H5ClOS and a molecular weight of 160.62 g/mol. It is widely utilized in pharmaceutical and agrochemical synthesis due to its reactive acetyl and chlorothiophene groups.

Physical Properties:

Property Value
Density 1.312 g/cm³
Melting Point 46–49°C
Boiling Point 233.3°C at 760 mmHg
Flash Point 108.3°C
Vapor Pressure 0.0562 mmHg at 25°C

Comparative Analysis:

Compound CAS Number Melting Point Key Difference
2-Acetyl-5-Chlorothiophene 6310-09-4 46–49°C Chlorine substitution at 5th position
2-Acetyl-4-Chlorothiophene 34730-20-6 N/A Chlorine substitution at 4th position
2-Acetyl-5-Bromothiophene 5370-25-2 93–97°C Bromine substituent instead of chlorine

2. Key Applications

  • Pharmaceutical Intermediates: Used in synthesizing antihistamines and antiviral agents.
  • Agrochemicals: Serves as a precursor for herbicides and fungicides.
  • Material Science: Modifies polymer properties in specialty coatings.
  • Research & Development: Applied in cross-coupling reactions for heterocyclic compound studies.

3. Usage Scenarios

Scenario 1: Antiviral Drug Synthesis

2-Acetyl-5-Chlorothiophene acts as a key intermediate in synthesizing nucleoside analogs, enhancing bioavailability through thiophene ring functionalization.

Scenario 2: Polymer Modification

Incorporated into polythiophene derivatives to improve electrical conductivity in organic semiconductors.

4. Client Case Studies

Case Study 1: PharmaTech Solutions

Challenge: Required a stable intermediate for a novel antihistamine.
Solution: Optimized a 3-step synthesis route using 2-Acetyl-5-Chlorothiophene, achieving 92% purity.
Result: Reduced production costs by 18% and accelerated time-to-market by 6 months.

Case Study 2: AgroChem Innovations

Challenge: Needed a cost-effective fungicide precursor.
Solution: Developed a scalable chlorothiophene derivatization process.
Result: Achieved 30% higher crop protection efficiency compared to traditional formulations.

5. Contact for Inquiries

For technical specifications, bulk pricing, or custom synthesis requests:
Email: info@vivalr.com
Phone: (86) 15866781826

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