3,5-BIS(METHYLSULFONYL)ANILINE

Comprehensive Guide to 3,5-BIS(METHYLSULFONYL)ANILINE

Table of Contents

• 1. Product Overview & Specifications
• 2. Applications & Industrial Uses
• 3. Usage Scenarios & Case Studies
• 4. Real Client Success Stories
• 5. Technical Support & Inquiry

1. Product Overview & Specifications

3,5-BIS(METHYLSULFONYL)ANILINE (CAS 100834-28-4) is a sulfonyl-substituted aniline derivative widely used in pharmaceutical intermediates and specialty chemical synthesis.

Key Parameters:

Comparative Analysis:

2. Applications & Industrial Uses

Primary Applications:

• Pharmaceutical Intermediate: Key building block for kinase inhibitors
• Agrochemicals: Precursor for sulfonylurea herbicides
• Polymer Chemistry: Cross-linking agent for specialty resins

Technical Advantages:

• Enhanced electron-withdrawing properties
• Improved thermal stability vs. non-sulfonated analogs
• Compatible with palladium-catalyzed coupling reactions

3. Usage Scenarios & Case Studies

Typical Reaction Workflow:

1. Buchwald-Hartwig amination with aryl halides
2. Suzuki-Miyaura cross-coupling applications
3. Preparation of sulfonamide-based drug candidates

Optimization Tips:

• Use degassed solvents for metal-catalyzed reactions
• Maintain reaction temperature below 80°C
• Recommended stoichiometry: 1.1-1.2 equivalents

4. Real Client Success Stories

Case Study 1: Oncology Drug Development

Client: European Pharma Research Group
Application: Synthesis of tyrosine kinase inhibitor intermediate
Result: Achieved 92% yield in Heck coupling reaction

Case Study 2: Advanced Material Production

Client: US Polymer Solutions Inc.
Application: Cross-linker for high-temperature resins
Result: Enhanced thermal stability by 40°C vs. previous formulation

5. Technical Support & Inquiry

For technical specifications, bulk pricing, or custom synthesis requirements:

• Email: info@vivalr.com
• Tel: (86) 15866781826

Request free sample or MSDS documentation:

• Fast response within 2 business hours
• Global shipping available
• Custom purity grades (98%-99.9%)