4-Nitropyridine N-oxide: Comprehensive Product Guide
Table of Contents
1. Product Overview & Specifications
Key Parameters
| Property | 4-Nitropyridine N-oxide | 3-Bromo Derivative | 3-Chloro Derivative |
|---|---|---|---|
| CAS Number | 1124-33-0 | 1678-49-5 | 76439-45-7 |
| Molecular Formula | C5H4N2O3 | C5H3BrN2O3 | C5H3ClN2O3 |
| Molecular Weight | 140.1 g/mol | 218.99 g/mol | 174.54 g/mol |
| Appearance | Light yellow crystalline powder | Off-white solid | Pale yellow crystals |
2. Applications & Use Cases
Pharmaceutical Intermediates
Widely used in synthesizing proton pump inhibitors (e.g., Lansoprazole) through controlled nitration and oxidation processes. Enables precise modification of drug candidates’ bioavailability.
Agrochemical Development
Critical precursor for creating targeted pesticides with enhanced stability against environmental degradation.
Research Applications
- Electron-deficient ligand in catalytic systems
- Building block for functionalized heterocycles
- Intermediate in fluorescent probe synthesis
3. Client Success Stories
Case 1: Pharmaceutical Manufacturer
Client: Aurobindo Pharma Ltd.
Challenge: Required high-purity (>99.5%) batches for GMP-compliant Lansoprazole production.
Solution: Custom synthesis with strict impurity profiling (HPLC <0.1% total impurities).
Outcome: 30% yield improvement vs. previous supplier.
Case 2: Research Institution
Client: Shanghai Institute of Materia Medica
Application: Development of novel kinase inhibitors
Results: Enabled synthesis of 15+ derivatives with IC50 values ≤50nM.
4. Technical Support & Inquiries
For product specifications, bulk pricing, or synthesis customization:
Email: info@vivalr.com
Tel: (86) 15866781826
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