4-HYDROXY-8-BROMOQUINOLINE

Product Name:4-HYDROXY-8-BROMOQUINOLINE
CAS:57798-00-2
MFC9H6BrNO
MW:224.05
EINECS:804-020-8
MOL File:57798-00-2.mol

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4-HYDROXY-8-BROMOQUINOLINE Product Guide

Table of Contents

1. Product Overview & Specifications

CAS Number: 39763-21-8
Molecular Formula: C9H6BrNO
Molecular Weight: 224.06 g/mol
Appearance: Off-white to yellow crystalline powder
Purity: ≥98% (HPLC)
Solubility: Soluble in DMSO, methanol, and ethanol

Parameter 4-HYDROXY-8-BROMOQUINOLINE Similar Compounds
Reactivity High bromine substitution selectivity Lower selectivity in non-brominated derivatives
Pharma Compatibility Ideal for kinase inhibitor synthesis Limited use in targeted therapies

2. Key Applications

Widely used in:

  • Pharmaceutical Intermediates: Synthesis of tyrosine kinase inhibitors (e.g., EGFR inhibitors)
  • Antimicrobial Research: Development of quinolone-based antibiotics
  • Material Science: Building block for OLED electron-transport layers

3. Usage Guidelines

  • Store at 2-8°C in airtight containers
  • Use under inert gas (N2/Ar) for moisture-sensitive reactions
  • Recommended solvent systems: DMF/DCM (1:3 ratio) for cross-coupling reactions

4. Case Studies

Case 1: Anticancer Drug Development
Application: Key intermediate in third-generation PARP inhibitor synthesis
Result: 92% yield improvement vs traditional routes

Case 2: OLED Material Innovation
Application: Electron-deficient moiety for blue-emitting layers
Result: Achieved 18% external quantum efficiency

5. Client Success Stories

Client A: Top 10 Pharma Company
Project: Scalable synthesis of BTK inhibitor candidates
Outcome: Reduced production costs by 35% through optimized bromination

Client B: Advanced Materials Startup
Project: Development of thermally stable electron transport materials
Outcome: Patent filed (US20230365821A1) with 150°C operational stability

6. Request a Quote

Contact our technical team for:

  • Custom synthesis options
  • Bulk pricing (50kg+ quantities available)
  • MSDS & regulatory support

Email: info@vivalr.com
Phone: (86) 15866781826

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