4-HYDROXY-8-BROMOQUINOLINE Product Guide
Table of Contents
- Product Overview & Specifications
- Key Applications
- Usage Guidelines
- Case Studies
- Client Success Stories
- Request a Quote
1. Product Overview & Specifications
CAS Number: 39763-21-8
Molecular Formula: C9H6BrNO
Molecular Weight: 224.06 g/mol
Appearance: Off-white to yellow crystalline powder
Purity: ≥98% (HPLC)
Solubility: Soluble in DMSO, methanol, and ethanol
| Parameter | 4-HYDROXY-8-BROMOQUINOLINE | Similar Compounds |
|---|---|---|
| Reactivity | High bromine substitution selectivity | Lower selectivity in non-brominated derivatives |
| Pharma Compatibility | Ideal for kinase inhibitor synthesis | Limited use in targeted therapies |
2. Key Applications
Widely used in:
- Pharmaceutical Intermediates: Synthesis of tyrosine kinase inhibitors (e.g., EGFR inhibitors)
- Antimicrobial Research: Development of quinolone-based antibiotics
- Material Science: Building block for OLED electron-transport layers
3. Usage Guidelines
- Store at 2-8°C in airtight containers
- Use under inert gas (N2/Ar) for moisture-sensitive reactions
- Recommended solvent systems: DMF/DCM (1:3 ratio) for cross-coupling reactions
4. Case Studies
Case 1: Anticancer Drug Development
Application: Key intermediate in third-generation PARP inhibitor synthesis
Result: 92% yield improvement vs traditional routes
Case 2: OLED Material Innovation
Application: Electron-deficient moiety for blue-emitting layers
Result: Achieved 18% external quantum efficiency
5. Client Success Stories
Client A: Top 10 Pharma Company
Project: Scalable synthesis of BTK inhibitor candidates
Outcome: Reduced production costs by 35% through optimized bromination
Client B: Advanced Materials Startup
Project: Development of thermally stable electron transport materials
Outcome: Patent filed (US20230365821A1) with 150°C operational stability
6. Request a Quote
Contact our technical team for:
- Custom synthesis options
- Bulk pricing (50kg+ quantities available)
- MSDS & regulatory support
Email: info@vivalr.com
Phone: (86) 15866781826


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